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How to Write and Publish a Research Paper for a Peer-Reviewed Journal

  • Open access
  • Published: 30 April 2020
  • Volume 36 , pages 909–913, ( 2021 )

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journal of research paper

  • Clara Busse   ORCID: orcid.org/0000-0002-0178-1000 1 &
  • Ella August   ORCID: orcid.org/0000-0001-5151-1036 1 , 2  

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Communicating research findings is an essential step in the research process. Often, peer-reviewed journals are the forum for such communication, yet many researchers are never taught how to write a publishable scientific paper. In this article, we explain the basic structure of a scientific paper and describe the information that should be included in each section. We also identify common pitfalls for each section and recommend strategies to avoid them. Further, we give advice about target journal selection and authorship. In the online resource 1 , we provide an example of a high-quality scientific paper, with annotations identifying the elements we describe in this article.

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Writing Skills

Avoid common mistakes on your manuscript.

Introduction

Writing a scientific paper is an important component of the research process, yet researchers often receive little formal training in scientific writing. This is especially true in low-resource settings. In this article, we explain why choosing a target journal is important, give advice about authorship, provide a basic structure for writing each section of a scientific paper, and describe common pitfalls and recommendations for each section. In the online resource 1 , we also include an annotated journal article that identifies the key elements and writing approaches that we detail here. Before you begin your research, make sure you have ethical clearance from all relevant ethical review boards.

Select a Target Journal Early in the Writing Process

We recommend that you select a “target journal” early in the writing process; a “target journal” is the journal to which you plan to submit your paper. Each journal has a set of core readers and you should tailor your writing to this readership. For example, if you plan to submit a manuscript about vaping during pregnancy to a pregnancy-focused journal, you will need to explain what vaping is because readers of this journal may not have a background in this topic. However, if you were to submit that same article to a tobacco journal, you would not need to provide as much background information about vaping.

Information about a journal’s core readership can be found on its website, usually in a section called “About this journal” or something similar. For example, the Journal of Cancer Education presents such information on the “Aims and Scope” page of its website, which can be found here: https://www.springer.com/journal/13187/aims-and-scope .

Peer reviewer guidelines from your target journal are an additional resource that can help you tailor your writing to the journal and provide additional advice about crafting an effective article [ 1 ]. These are not always available, but it is worth a quick web search to find out.

Identify Author Roles Early in the Process

Early in the writing process, identify authors, determine the order of authors, and discuss the responsibilities of each author. Standard author responsibilities have been identified by The International Committee of Medical Journal Editors (ICMJE) [ 2 ]. To set clear expectations about each team member’s responsibilities and prevent errors in communication, we also suggest outlining more detailed roles, such as who will draft each section of the manuscript, write the abstract, submit the paper electronically, serve as corresponding author, and write the cover letter. It is best to formalize this agreement in writing after discussing it, circulating the document to the author team for approval. We suggest creating a title page on which all authors are listed in the agreed-upon order. It may be necessary to adjust authorship roles and order during the development of the paper. If a new author order is agreed upon, be sure to update the title page in the manuscript draft.

In the case where multiple papers will result from a single study, authors should discuss who will author each paper. Additionally, authors should agree on a deadline for each paper and the lead author should take responsibility for producing an initial draft by this deadline.

Structure of the Introduction Section

The introduction section should be approximately three to five paragraphs in length. Look at examples from your target journal to decide the appropriate length. This section should include the elements shown in Fig.  1 . Begin with a general context, narrowing to the specific focus of the paper. Include five main elements: why your research is important, what is already known about the topic, the “gap” or what is not yet known about the topic, why it is important to learn the new information that your research adds, and the specific research aim(s) that your paper addresses. Your research aim should address the gap you identified. Be sure to add enough background information to enable readers to understand your study. Table 1 provides common introduction section pitfalls and recommendations for addressing them.

figure 1

The main elements of the introduction section of an original research article. Often, the elements overlap

Methods Section

The purpose of the methods section is twofold: to explain how the study was done in enough detail to enable its replication and to provide enough contextual detail to enable readers to understand and interpret the results. In general, the essential elements of a methods section are the following: a description of the setting and participants, the study design and timing, the recruitment and sampling, the data collection process, the dataset, the dependent and independent variables, the covariates, the analytic approach for each research objective, and the ethical approval. The hallmark of an exemplary methods section is the justification of why each method was used. Table 2 provides common methods section pitfalls and recommendations for addressing them.

Results Section

The focus of the results section should be associations, or lack thereof, rather than statistical tests. Two considerations should guide your writing here. First, the results should present answers to each part of the research aim. Second, return to the methods section to ensure that the analysis and variables for each result have been explained.

Begin the results section by describing the number of participants in the final sample and details such as the number who were approached to participate, the proportion who were eligible and who enrolled, and the number of participants who dropped out. The next part of the results should describe the participant characteristics. After that, you may organize your results by the aim or by putting the most exciting results first. Do not forget to report your non-significant associations. These are still findings.

Tables and figures capture the reader’s attention and efficiently communicate your main findings [ 3 ]. Each table and figure should have a clear message and should complement, rather than repeat, the text. Tables and figures should communicate all salient details necessary for a reader to understand the findings without consulting the text. Include information on comparisons and tests, as well as information about the sample and timing of the study in the title, legend, or in a footnote. Note that figures are often more visually interesting than tables, so if it is feasible to make a figure, make a figure. To avoid confusing the reader, either avoid abbreviations in tables and figures, or define them in a footnote. Note that there should not be citations in the results section and you should not interpret results here. Table 3 provides common results section pitfalls and recommendations for addressing them.

Discussion Section

Opposite the introduction section, the discussion should take the form of a right-side-up triangle beginning with interpretation of your results and moving to general implications (Fig.  2 ). This section typically begins with a restatement of the main findings, which can usually be accomplished with a few carefully-crafted sentences.

figure 2

Major elements of the discussion section of an original research article. Often, the elements overlap

Next, interpret the meaning or explain the significance of your results, lifting the reader’s gaze from the study’s specific findings to more general applications. Then, compare these study findings with other research. Are these findings in agreement or disagreement with those from other studies? Does this study impart additional nuance to well-accepted theories? Situate your findings within the broader context of scientific literature, then explain the pathways or mechanisms that might give rise to, or explain, the results.

Journals vary in their approach to strengths and limitations sections: some are embedded paragraphs within the discussion section, while some mandate separate section headings. Keep in mind that every study has strengths and limitations. Candidly reporting yours helps readers to correctly interpret your research findings.

The next element of the discussion is a summary of the potential impacts and applications of the research. Should these results be used to optimally design an intervention? Does the work have implications for clinical protocols or public policy? These considerations will help the reader to further grasp the possible impacts of the presented work.

Finally, the discussion should conclude with specific suggestions for future work. Here, you have an opportunity to illuminate specific gaps in the literature that compel further study. Avoid the phrase “future research is necessary” because the recommendation is too general to be helpful to readers. Instead, provide substantive and specific recommendations for future studies. Table 4 provides common discussion section pitfalls and recommendations for addressing them.

Follow the Journal’s Author Guidelines

After you select a target journal, identify the journal’s author guidelines to guide the formatting of your manuscript and references. Author guidelines will often (but not always) include instructions for titles, cover letters, and other components of a manuscript submission. Read the guidelines carefully. If you do not follow the guidelines, your article will be sent back to you.

Finally, do not submit your paper to more than one journal at a time. Even if this is not explicitly stated in the author guidelines of your target journal, it is considered inappropriate and unprofessional.

Your title should invite readers to continue reading beyond the first page [ 4 , 5 ]. It should be informative and interesting. Consider describing the independent and dependent variables, the population and setting, the study design, the timing, and even the main result in your title. Because the focus of the paper can change as you write and revise, we recommend you wait until you have finished writing your paper before composing the title.

Be sure that the title is useful for potential readers searching for your topic. The keywords you select should complement those in your title to maximize the likelihood that a researcher will find your paper through a database search. Avoid using abbreviations in your title unless they are very well known, such as SNP, because it is more likely that someone will use a complete word rather than an abbreviation as a search term to help readers find your paper.

After you have written a complete draft, use the checklist (Fig. 3 ) below to guide your revisions and editing. Additional resources are available on writing the abstract and citing references [ 5 ]. When you feel that your work is ready, ask a trusted colleague or two to read the work and provide informal feedback. The box below provides a checklist that summarizes the key points offered in this article.

figure 3

Checklist for manuscript quality

Data Availability

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Vetto JT (2014) Short and sweet: a short course on concise medical writing. J Cancer Educ 29(1):194–195

Brett M, Kording K (2017) Ten simple rules for structuring papers. PLoS ComputBiol. https://doi.org/10.1371/journal.pcbi.1005619

Lang TA (2017) Writing a better research article. J Public Health Emerg. https://doi.org/10.21037/jphe.2017.11.06

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Acknowledgments

Ella August is grateful to the Sustainable Sciences Institute for mentoring her in training researchers on writing and publishing their research.

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Busse, C., August, E. How to Write and Publish a Research Paper for a Peer-Reviewed Journal. J Canc Educ 36 , 909–913 (2021). https://doi.org/10.1007/s13187-020-01751-z

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Ultraviolet radiation technologies and healthcare associated infections: standards and metrology needs     dianne l. poster, c. cameron miller, richard a. martinello, norman r. horn, michael t. postek, troy e. cowan, yaw s. obeng, john j. kasianowicz  https://doi.org/10.6028/jres.126.014   published august 20, 2021  supplementary material:  https://doi.org/10.6028/jres.126.014s&nbsp ;, perspectives and recommendations regarding standards for ultraviolet-c whole-room disinfection in healthcare   arthur kreitenberg and richard a. martinello  https://doi.org/10.6028/jres.126.015   published august 20, 2021 , methods and mechanisms of photonic disinfection   daniel b. spicer  https://doi.org/10.6028/jres.126.016   published august 20, 2021 , comparison of reflective properties of materials exposed to ultraviolet-c radiation   pawel de sternberg stojalowski and jonathan fairfoull  https://doi.org/10.6028/jres.126.017   published august 20, 2021 , sars-cov-2 ultraviolet radiation dose-response behavio r  ernest r. blatchley iii, brian petri, wenjun sun  https://doi.org/10.6028/jres.126.018   published august 20, 2021 , effects of ultraviolet-c radiation exposure on aircraft cabin materials   stephen f. yates, giorgio isella, emir rahislic, spencer barbour, lillian tiznado  https://doi.org/10.6028/jres.126.019   published august 20, 2021 , best practices for germicidal ultraviolet-c dose measurement for n95 respirator decontamination   alisha geldert, halleh b. balch, anjali gopal, alison su, samantha m. grist, amy e. herr  https://doi.org/10.6028/jres.126.020   published august 20, 2021 , sensitivity of bacteria, protozoa, viruses, and other microorganisms to ultraviolet radiation   mahsa masjoudi, madjid mohseni, james r. bolton  https://doi.org/10.6028/jres.126.021   published august 20, 2021 , broadband dielectric spectroscopy as a potential label-free method to rapidly verify ultraviolet-c radiation disinfection    yaw s. obeng, brian j. nablo, darwin r. reyes, dianne l. poster, michael t. postek  https://doi.org/10.6028/jres.126.022   published august 20, 2021 , efficacy of ultraviolet-c devices for the disinfection of personal protective equipment fabrics and n95 respirators   kumari moothedath chandran, praveen c. ramamurthy, kawkab kanjo, rohan narayan, s. raghu menon  https://doi.org/10.6028/jres.126.023   published august 20, 2021 , estimation of the ultraviolet-c doses from mercury lamps and light-emitting diodes required to disinfect surfaces   pablo fredes, ulrich raff, ernesto gramsch, marcelo tarkowski  https://doi.org/10.6028/jres.126.025   published august 20, 2021 , mean differential continuous pulse method for accurate optical measurements of light-emitting diodes and laser diodes yuqin zong, jeff hulett, naomasa koide, yoshiki yamaji, c. cameron miller https://doi.org/10.6028/jres.126.034 published november 23, 2021, design considerations for a surface disinfection device using ultraviolet-c light-emitting diodes pratibha sharma, pao chen, saya han, peter chung, jungpin chen, justin tseng, chang han https://doi.org/10.6028/jres.126.045 published february 16, 2022, inactivation of pathogens in air using ultraviolet direct irradiation below exposure limits gary r. allen, kevin j. benner, william p. bahnfleth https://doi.org/10.6028/jres.126.052 published march 1, 2022, portable ultraviolet-c chambers for inactivation of sars-cov-2 shelby claytor, roger campbell, ashton hattori, eric brown, christopher hollis, max schureck, howard atchley, john stone, michael grady, benjamin yang, and t. robert harris https://doi.org/10.6028/jres.126.056 published march 18, 2022, capacity models and transmission risk mitigation: an engineering framework to predict the effect of air disinfection by germicidal ultraviolet radiation sam rhea sarcia https://doi.org/10.6028/jres.126.057 published march 21, 2022, disinfection of respirators with ultraviolet radiation dianne l. poster, matthew hardwick, c. cameron miller, michael a. riley, w.w. shanaka i. rodrigo, andras e. vladar, john d. wright, christopher d. zangmeister, clarence zarobila, jeremy starkweather, john wynne, jason yilzarde https://doi.org/10.6028/jres.126.058 published march 25, 2022, models for an ultraviolet-c research and development consortium dianne l. poster, michael t. postek, yaw s. obeng, john j. kasianowicz, troy e. cowan, norman r. horn, c. cameron miller,  richard a. martinello https://doi.org/10.6028/jres.126.055 published march 25, 2022.

Calorimetry in Computed Tomography Beams H. Heather Chen-Mayer, Ronald E. Tosh, Fred B. Bateman, Paul M. Bergstrom, Brian E. Zimmerman https://doi.org/10.6028/jres.126.054 Published March 10, 2022

Keyphrase Extraction for Technical Language Processing Alden Dima and Aaron Massey https://doi.org/10.6028/jres.126.053 Published March 9, 2022

The NIST Vacuum Double-Crystal Spectrometer: A Tool for SI-Traceable Measurement of X-Ray Emission Spectra Csilla I. Szabo, James P. Cline, Albert Henins, Lawrence T. Hudson, Marcus H. Mendenhall https://doi.org/10.6028/jres.126.049 Published March 9, 2022

Porosity, Powder X-Ray Diffraction Patterns, Skeletal Density, and Thermal Stability of NIST Zeolitic Reference Materials RM 8850, RM 8851, and RM 8852 Huong Giang T. Nguyen, Ran Tao, Roger D. van Zee https://doi.org/10.6028/jres.126.047 Published March 1, 2022

Toward a New Primary Standardization of Radionuclide Massic Activity Using Microcalorimetry and Quantitative Milligram-Scale Samples Ryan P. Fitzgerald, Bradley K. Alpert, Daniel T. Becker, Denis E. Bergeron, Richard M. Essex, Kelsey Morgan, Svetlana Nour, Galen O’Neil, Dan R. Schmidt, Gordon A. Shaw, Daniel Swetz, R. Michael Verkouteren, Daikang Yan https://doi.org/10.6028/jres.126.048 Published February 24, 2022

Acceptance Testing Methodology for the Production of Standard Reference Material 2806: Medium Test Dust in Hydraulic Fluid Robert Fletcher, James Filliben, Nicholas Ritchie, Nicolas Petillon https://doi.org/10.6028/jres.126.044 Published February 24, 2022

Understanding Deformation Behavior in Uniaxial Tensile Tests of Steel Specimens at Varying Strain Rates Dilip K. Banerjee, Mark A. Iadicola, Adam Creuziger https://doi.org/10.6028/jres.126.050 Published February 22, 2022

The National Bureau of Standards and the Radium Dial Painters Bert M. Coursey https://doi.org/10.6028/jres.126.051 Published February 14, 2022

Feasibility of Modeling Orthogonal Frequency-Division Multiplexing Communication Signals with Unsupervised Generative Adversarial Networks Jack Sklar and Adam Wunderlich https://doi.org/10.6028/jres.126.046 Published February 14, 2022

Development and Evaluation of Bluetooth Low-Energy Device for Electronic Encounter Metrics Kathryn E. Keenan, José Aumentado, Harold Booth, Kimberly A. Briggman, Mikail Kraft, Michele N. Martin, René C. Peralta, Angela Y. Robinson, Krister Shalm, Michelle S. Stephens, Emily A. Townsend, Sae Woo Nam https://doi.org/10.6028/jres.126.043 Published January 20, 2022

ASME B89.4.23 Performance Evaluation Tests and Geometry Errors in X-Ray Computed Tomography Systems Bala Muralikrishnan, Meghan Shilling, Vincent Lee https://doi.org/10.6028/jres.126.042 Published January 20, 2022

Multi-Source Common-View Disciplined Clock: A Fail-Safe Clock for Critical Infrastructure Systems Michael A. Lombardi https://doi.org/10.6028/jres.126.041 Published January 10, 2022

Optical Fiber Time Delay Comparison Between NIST and LAMETRO T. Dennis and J. Jimenez https://doi.org/10.6028/jres.126.040 Published January 10, 2022

Type B Uncertainty Analysis of Gravity-Based Determinations of Triaxial-Accelerometer Properties by Simulation of Measurement Errors Jon Geist and Michael Gaitan https://doi.org/10.6028/jres.126.038 Published January 4, 2022

Estimation of a Minimum Allowable Structural Strength Based on Uncertainty in Material Test Data Jeffrey T. Fong, N. Alan Heckert, James J. Filliben, Pedro V. Marcal, Stephen W. Freiman https://doi.org/10.6028/jres.126.036 Published December 7, 2021

Precise Numerical Differentiation of Thermodynamic Functions with Multicomplex Variables Ulrich K. Deiters and Ian H. Bell https://doi.org/10.6028/jres.126.033 Published November 29, 2021

Ratio-Based Pulse Shape Discrimination: Analytic Results for Gaussian and Poisson Noise Models Kevin J Coakley https://doi.org/10.6028/jres.126.032 Published November 9, 2021

X-Ray Computed Tomography Instrument Performance Evaluation, Part III: Sensitivity to Detector Geometry and Rotation Stage Errors at Different Magnifications Prashanth Jaganmohan, Bala Muralikrishnan, Meghan Shilling, Edward Morse https://doi.org/10.6028/jres.126.029 Published September 29, 2021

Dynamic Plasticity Model for Rapidly Heated 1045 Steel Up to 1000 °C Steven P. Mates and Sheng-Yen Li https://doi.org/10.6028/jres.126.026 Published August 27, 2021

Development of the Advanced Encryption Standard Miles E. Smid https://doi.org/10.6028/jres.126.024 Published August 16, 2021

Measurement Uncertainty of Surface Temperature Distributions for Laser Powder Bed Fusion Processes David C. Deisenroth, Sergey Mekhontsev, Brandon Lane, Leonard Hanssen, Ivan Zhirnov, Vladimir Khromchenko, Steven Grantham, Daniel Cardenas-Garcia, Alkan Donmez https://doi.org/10.6028/jres.126.013 Published August 10, 2021

Optical Power Scale Realization by Laser Calorimeter after 45 Years of Operation Matthew T. Spidell and Anna K. Vaskuri https://doi.org/10.6028/jres.126.011 Published June 28, 2021

Exact Tile-Based Segmentation Inference for Images Larger than GPU Memory Michael Majurski and Peter Bajcsy https://doi.org/10.6028/jres.126.009 Published June 3, 2021

Decision Tree for Key Comparisons Antonio Possolo, Amanda Koepke, David Newton, Michael R. Winchester https://doi.org/10.6028/jres.126.007 Published April 27, 2021

Generative Adversarial Network Performance in Low-Dimensional Settings Felix Jimenez, Amanda Koepke, Mary Gregg, Michael Frey https://doi.org/10.6028/jres.126.008 Published April 20, 2021

Evaluations of a Detector-Limited Digital Impedance Bridge Mona Feige, Stephan Schlamminger, Bryan Waltrip, Michael Berilla, Yicheng Wang https://doi.org/10.6028/jres.126.006 Published April 6, 2021

Encounter Metrics and Exposure Notification  René Peralta and Angela Robinson https://doi.org/10.6028/jres.126.003 Published March 28, 2021

Coverage Intervals Sara Stoudt, Adam Pintar, Antonio Possolo https://doi.org/10.6028/jres.126.004 Published March 3, 2021

Seabird Tissue Archival and Monitoring Project (STAMP) Data from 1999-2010 Nathan A. Mahynski, Jared M. Ragland, Stacy S. Schuur, Rebecca Pugh, Vincent K. Shen https://doi.org/10.6028/jres.126.028 Published December 17, 2021 Data:  https://doi.org/10.18434/mds2-2431

Digitization of Adsorption Isotherms from "The Thermodynamics and Hysteresis of Adsorption" Daniel W. Siderius https://doi.org/10.6028/jres.126.037 Published December 16, 2021 Data:  https://doi.org/10.18434/mds2-2466

An Analysis of an Inventory of Community Resilience Frameworks Jarrod Loerzel and Maria Dillard https://doi.org/10.6028/jres.126.031 Published October 20, 2021 Data:  https://doi.org/10.18434/mds2-2297

Translator from Extended SysML to Physical Interaction and Signal Flow Simulation Platforms, Version 1.1 Raphael Barbau, Conrad Bock, Mehdi Dadfarnia https://doi.org/10.6028/jres.126.027 Published September 22, 2021 Data:  https://doi.org/10.18434/mds2-2414

Atomic Model Structure of the NIST Monoclonal Antibody (NISTmAb) Reference Material Christina Bergonzo and D. Travis Gallagher https://doi.org/10.6028/jres.126.012 Published July 15, 2021 Data:  https://doi.org/10.18434/mds2-2396

Dataset from HDX-MS Studies of IgG1 Glycoforms and Their Interactions with the FcγRIa (CD64) Receptor Kyle W. Anderson, Kerry Scott, Ioannis L. Karageorgos, Elyssia S. Gallagher, Venkata S. Tayi, Michael Butler, Jeffrey W. Hudgens https://doi.org/10.6028/jres.126.010 Published June 17, 2021 Data:  https://doi.org/10.18434/mds2-2365

In Situ Thermography During Laser Powder Bed Fusion of a Nickel Superalloy 625 Artifact with Various Overhangs and Supports Benjamin Molnar, Jarred C. Heigel, Eric Whitenton https://doi.org/10.6028/jres.126.005 Published March 12, 2021 Data:  https://doi.org/10.18434/M32112

AbsorbanceQ: An App for Generating Absorbance Images from Brightfield Images Stephen M. Zimmerman, Carl G. Simon, Jr., Greta Babakhanova https://doi.org/10.6028/jres.126.039 Published January 4, 2022 Software:  https://doi.org/10.18434/mds2-2423

The NMR Spectral Measurement Database: A System for Organizing and Accessing NMR Spectra of Therapeutic Proteins Niksa Blonder and Frank Delaglio https://doi.org/10.6028/jres.126.035 Published December 16, 2021 Software:  https://doi.org/10.18434/mds2-2495

Optbayesexpt: Sequential Bayesian Experiment Design for Adaptive Measurements Robert D. McMichael, Sean M. Blakley, Sergey Dushenko https://doi.org/10.6028/jres.126.002 Published February 3, 2021 Software: https://doi.org/10.18434/M32230

A Review of Models for Heat Transfer in Steel and Concrete Members During Fire Dilip K. Banerjee https://doi.org/10.6028/jres.126.030 Published October 22, 2021

DNA Origami Design: A How-To Tutorial Jacob M. Majikes and J. Alexander Liddle https://doi.org/10.6028/jres.126.001 Published January 8, 2021

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Neural Representations of Sensory Uncertainty and Confidence are Associated with Perceptual Curiosity

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Humans are immensely curious and motivated to reduce uncertainty, but little is known about the neural mechanisms that generate curiosity. Curiosity is inversely associated with confidence, suggesting that it is triggered by states of low confidence (subjective uncertainty). The neural mechanisms of this process, however, have been little investigated. What are the mechanisms through which uncertainty about an event gives rise to curiosity about that event? Inspired by studies of sensory uncertainty, we hypothesized that visual areas provide multivariate representations of uncertainty, which are then read out by higher-order structures to generate signals of confidence and, ultimately, trigger curiosity. During fMRI, participants (17 female, 15 male) performed a new task in which they rated their confidence in identifying distorted images of animals and objects and their curiosity to see the clear image. To link sensory certainty and curiosity, we measured the activity evoked by each image in occipitotemporal cortex (OTC) and devised a new metric of “OTC Certainty” indicating the strength of evidence this activity conveys about the animal vs. object categories. We show that, consistent with findings using trivia questions, perceptual curiosity peaked at low confidence. Moreover, OTC Certainty negatively correlated with curiosity, establishing a link between curiosity and a multivariate representation of sensory uncertainty. Finally, univariate (average) activity in two frontal areas – vmPFC and ACC – correlated positively with confidence and negatively with curiosity, and the vmPFC mediated the relationship between OTC Certainty and curiosity. The results suggest that multiple mechanisms link curiosity with representations of confidence and uncertainty.

Significance Statement Curiosity motivates us to explore and learn about the world around us. Traditional perspectives hypothesize that curiosity arises from variability in confidence, but the neural mechanisms by which this occurs have been difficult to evaluate. Here, we harness the human visual system to uncover a neural mechanism of curiosity. We show that a multivariate representation of certainty in occitotemporal cortex is transformed into a univariate representation of confidence in prefrontal cortex to facilitate curiosity. Together, these results illuminate how perceptual input is transformed by successive neural representations to ultimately evoke a feeling of curiosity - elucidating how and why we become curious to learn and delve into diverse domains of knowledge.

The research described in this paper was supported by the National Institute of Mental Health as part of the National Research Service Award (Grant #:1F31MH125589), and the Zuckerman Institute MR Seed Grant Award (Grant #: CU-ZI-MR-S-0017) both awarded to Michael Cohanpour. We thank the Alyssano Group, Gottlieb Lab, Kriegeskorte Lab, Christopher Baldassano, Janet Metcalfe, and Yasmine El-Shamayleh for their valuable insight on this project; Ray Lee and Noreen Violante for their technical support with the MRI scanner; and Serra Favila, Heiko Schütt, and Javier Domínguez Zamora for their crucial revisions to the manuscript.

The authors declare that they have no conflict of interest.

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This paper is in the following e-collection/theme issue:

Published on 15.7.2024 in Vol 26 (2024)

The Use of Telepsychiatry Services in Emergency Settings: Scoping Review

Authors of this article:

Author Orcid Image

  • Ligat Shalev 1 , PhD   ; 
  • Renana Eitan 2 * , MD   ; 
  • Adam J Rose 1 * , MSc, MD  

1 School of Public Health, Hebrew University, Jerusalem, Israel

2 Psychiatric Division, Sourasky Medical Center, Tel Aviv-Yafo, Israel

*these authors contributed equally

Corresponding Author:

Ligat Shalev, PhD

School of Public Health, Hebrew University

Ein Kerem Campus

Jerusalem, 91120

Phone: 972 0507554025

Email: [email protected]

Background: Telepsychiatry (TP), a live video meeting, has been implemented in many contexts and settings. It has a distinct advantage in the psychiatric emergency department (ED) setting, as it expedites expert assessments for psychiatric patients. However, limited knowledge exits for TP’s effectiveness in the ED setting, as well as the process of implementing TP in this setting.

Objective: This scoping review aimed to review the existing evidence for the administrative and clinical outcomes for TP in the ED setting and to identify the barriers and facilitators to implementing TP in this setting.

Methods: The scoping review was conducted according to the guidelines for the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Three electronic databases were examined: PubMed, Embase, and Web of Science. The databases were searched from January 2013 to April 2023 for papers and their bibliography. A total of 2816 potentially relevant papers were retrieved from the initial search. Studies were screened and selected independently by 2 authors.

Results: A total of 11 articles were included. Ten papers reported on administrative and clinical outcomes of TP use in the ED setting and 1 on the barriers and facilitators of its implementation. TP is used in urban and rural areas and for settings with and with no on-site psychiatric services. Evidence shows that TP reduced waiting time for psychiatric evaluation, but in some studies, it was associated with prolonged total length of stay in the ED compared with in-person evaluation. Findings indicate lower admission rates in patients assessed with TP in the ED. Limited data were reported for TP costs, its use for involuntary commitment evaluations, and its use for particular subgroups of patients (eg, those with a particular diagnosis). A single paper examined TP implementation process in the ED, which explored the barriers and facilitators for implementation among patients and staff in a rural setting.

Conclusions: Based on the extant studies, TP seems to be generally feasible and acceptable to key stakeholders. However, this review detected a gap in the literature regarding TP’s effectiveness and implementation process in the ED setting. Specific attention should be paid to the examination of this service for specific groups of patients, as well as its use to enable assessments for possible involuntary commitment.

Introduction

Telepsychiatry use over the years.

The history of telepsychiatry (TP) began with doubts about its use [ 1 , 2 ]. While there are still questions about TP, it has gained increasing acceptance in recent years, as reflected through changes in relevant regulations [ 3 ]. TP is used for psychiatric assessment, treatment, and follow-up [ 4 ]. So far, the most prevalent technologies used for TP are by telephone [ 5 ], email [ 6 ], or recorded or live videos and hybrid models [ 7 ]. TP is used in the private [ 8 ] and public sectors, including for primary care [ 9 ] and secondary care [ 10 ]. TP has also been delivered in clinical settings [ 10 ] and in patients’ home environments [ 11 ]. TP has been used to treat different mental health conditions, and in different situations, including suicide attempts, self-harm, schizophrenia, and dual diagnosis of mental health conditions with substance abuse [ 12 ]. TP has been adapted to different treatment approaches, including for individuals [ 13 ] and group sessions [ 14 ]. TP has been used in both urban [ 15 ] and rural areas [ 11 ].

Current Evidence for Effectiveness of TP and Regarding Its Implementation

Various studies have examined the effectiveness of TP, often compared with face-to-face treatment approaches. In terms of accuracy of diagnosis and treatment decisions, TP has been shown to be as accurate as meeting with patients in person [ 16 , 17 ]. Using TP has been shown to reduce emergency department (ED) length of stay (LOS) by allowing more rapid access to psychiatric expertise [ 17 ]. For similar reasons, TP has been shown to reduce admission rates [ 18 ]. TP has been used to provide on-site psychiatric services to hospitals that previously did not have any [ 19 ]. Both patients [ 20 ] and providers [ 17 ] showed high satisfaction rates.

TP has also been examined using cost-effectiveness analyses [ 21 ], and at least some studies have found that it is cost saving compared with usual care [ 22 , 23 ]. Other studies have examined the process of implementing TP in different settings [ 9 , 24 - 26 ]. For example, some studies have detailed the experience of implementing remote mental health consultations during the COVID-19 [ 27 ], or reasons why some ED directors are avoiding the use of remote services, including TP [ 28 ].

Specific Challenges When Using TP for Psychiatric Emergencies

TP has advantages for general use, but it may have a particularly important role in addressing psychiatric emergencies. Most people find the ED an uncomfortable place to be [ 29 ]. However, for patients experiencing psychiatric emergencies, the ED may be even worse. The ED may exacerbate patients’ agitation, which may put health care providers or other bystanders at risk for violence [ 29 ]. In addition to this immediate effect, the ED can also have a long-term effect on psychiatric patients. Faessler and colleagues [ 30 ] found that psychological distress could last up to 30 days after ED discharge for patients with psychiatric disorders. Considering these data, TP may be a highly useful solution for ED settings, if it can help minimize patients’ time in the ED [ 31 ].

In the last few years, several reviews summarized the current evidence of TP services in the ED setting. One study reviewed the current data on acute situations but included not just psychiatric services but other practices and also included home-based services in addition to the ED setting [ 11 ]. A second review examined the barriers and facilitators of implementing TP, but most of the studies that were included did not focus on the use of TP for emergency settings [ 26 ]. A third study reviewed TP interventions in emergency and crisis situations, but this review included studies published more than a decade ago, when video-link technology was much less developed [ 32 ]. Thus, no updated published review of TP use for adult emergencies is available.

TP may bridge critical gaps in mental health care access and quality, addressing key issues, such as prolonged waiting times or workforce shortages, that hinder timely and effective patient care. Thus, TP has considerable potential to help improve service delivery and outcomes in mental health. To our knowledge, reviews assessing the use of TP in emergency settings in the past 10 years have not been conducted. Given the limited evidence, the objectives of this review were to search the literature on psychiatric live video meeting in emergency settings, to assess the overall findings regarding clinical and implementation outcomes, and to enumerate the barriers and facilitators for successful implementation.

We conducted this scoping review following the methodological guidance proposed by Arksey and O’Malley [ 33 ], Levac et al [ 34 ], and The Joanna Briggs Institute Reviewers’ Manual [ 35 ]. The 5 stages used in this scoping review were based on guidelines from Arksey and O’Malley: (1) identifying the research question; (2) identifying the relevant studies; (3) study selection; (4) charting the data; and (5) collating, summarizing, and reporting the results [ 33 ]. Our study focused on the current administrative and clinical evidence regarding the use of TP services in the ED setting, as well as the factors affecting their implementation in the ED setting. The reporting of this scoping review was guided by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) extension for Scoping Reviews (PRISMA-ScR) checklist [ 36 ] ( Multimedia Appendix 1 ).

Search Strategy

We searched 3 electronic databases, including PubMed, Embase, and Web of Science, using the following terms and combinations: (1) psychiatry, mental health, mental disorder, mental health care, and mental disease; (2) telepsychiatry, telemedicine, virtual medicine, tele health, eHealth, telecare, tele emergency, and digital mental health; and (3) video, video conference, videoconferencing, conference meeting, streaming, zoom, remote consultation, long distance consultation, distance counseling, eCounseling, and web-based counseling ( Multimedia Appendix 2 ).

Inclusion and Exclusion Criteria

Studies were included based on the inclusion and exclusion criteria, and if they met the population, concept, and context categorization recommended by The Joanna Briggs Institute [ 35 ] ( Table 1 ). We included studies focused on individuals 18 years of age and older who had a psychiatric session. Due to the different nature of the following patient groups, they were excluded from the search: children, couple or group sessions, and patients who have been arrested or convicted. While it was allowable for the clinician to address substance abuse as part of the service, we did not include studies solely addressing substance abuse issues. We also focused solely on 2-way video assessment and excluded other modes of communication such as telephone or asynchronous text messages.

We did make an exception to our rule about patient ages to include 3 especially important and broad-based studies. These studies were conducted nationwide [ 37 , 38 ] and statewide [ 15 ] and involved patients of all ages. We also focused on studies conducted within the past 10 years, due to significant advances in video-link technology around that time. We focused on the dates of data collection rather than publication, since a variable period may elapse between data collection and publication. Two studies started data collection on October 2012 for and finished collecting data years later; we decided to include these studies [ 39 , 40 ].

Inclusion criteriaExclusion criteria

Patients who are 18 years of age and older or ED staff that use and report about the telepsychiatry service based on direct experience

Individuals

Psychiatry services

Use of live video communication

Emergency settings

Qualitative, quantitative, or mixed methods studies. Quantitative studies must describe results of at least 30 participants

Empirical data with detailed methodology presented in journals, editorials, commentaries, letters to the editor, or scientific reports

Studies that use one of the following designs: observational and experimental, cross-sectional, or longitudinal; randomized controlled trials, nonrandomized or noncontrolled trials

Data collected during the past 10 years (from 2013)

English

a ED: emergency department.

b Not applicable.

Screening and Selection of Studies

The initial search of the 3 databases yielded 2,686 results. The hand search of the selected papers’ bibliography identified 130 additional records. After duplicates were removed, 1967 (69.8%) records were reviewed. The titles and abstracts of 69.8% (1967/2816) of the articles were screened, and 89.2% (1754/1967) of the articles were excluded as being not relevant. LS performed the initial screening to identify articles that were clearly not relevant, keeping articles that were questionably relevant or probably relevant. Then LS and AR performed independent full-text review of the 213 retained articles. A total of 94.8% (202/213) articles were excluded based on the reasons shown in Figure 1 . A total of 11 publications were ultimately included in the scoping review. In case of disagreement, LS and AR discussed the article until agreement was reached. The reasons for exclusion, as well as the entire selection procedure, are shown in the PRISMA flow diagram ( Figure 1 ).

journal of research paper

Charting the Data

The articles included in this scoping review were reviewed and results were recorded using a Microsoft Excel (Microsoft Corp) data charting table. The table included general information about the study characteristics (authors, publication year, title, data collection period, country, study purpose, study design, setting, and sample), a description of the TP service and usual care if applicable, outcome measures (administrative and clinical or process outcomes), and main study results.

Collating, Summarizing, and Reporting the Results

Included studies were examined thoroughly to understand similarities and differences. We had the following main categories of study outcomes: (1) administrative outcomes (eg, ED LOS, or mental illness spending); (2) clinical outcomes (eg, admission disposition or patient and providers satisfaction); and (3) process outcomes of TP implementation.

A total of 11 articles were included for data extraction in this scoping review, as can be seen in the PRISMA flowchart ( Figure 1 ).

Characteristics of the Studies

Although the search strategy was from January 2013 to April 2023, the studies that were identified and included collected data between October 2012 and 2023, and were published between 2015 and 2023. Of the 11 articles, 9 were published in the United States [ 15 , 19 , 37 - 43 ],1 in Australia [ 44 ], and 1 in Israel [ 45 ]. Of the 11 studies, 10 [ 15 , 19 , 37 - 43 , 45 ] were quantitative studies that examined administrative or clinical measurements of TP use, and 1 was a qualitative study that examined process outcomes [ 44 ]. Of the 10 quantitative studies, 3 were non–randomized controlled studies [ 40 , 41 , 45 ], 3 cross-sectional studies [ 15 , 19 , 38 ], 3 cohort studies [ 37 , 39 , 43 ], and 1 randomized controlled study [ 42 ] ( Table 2 ).

In the next section, we will summarize the results of our review, organized by our 2 main research questions, namely (1) to review the existing evidence for both administrative and clinical outcomes of TP in the ED setting and (2) to identify the known barriers and facilitators to implementing TP in this setting.

First research question: what is the existing evidence for both administrative and clinical outcomes of TP in the ED setting?
Authors (years)CountriesStudy objectiveSettingStudy sampleMethods (study paradigm, design, and tools)Main outcomes measures and special characteristics
Freeman et al (2023) [ ]United StatesTo investigate ED TP usage in the pre–COVID-19 era
Bistre et al (2022) [ ]IsraelTo evaluate the reliability and acceptability of TP assessments compared with in-person for involuntary admissions study
Patel et al (2022) [ ]United StatesTo assess the impact of a TP service compared with in-person in EDs on admissions, mental illness spending, ED LOS, mental illness outpatient follow-up care, and mortality
Saeed et al (2022) [ ]United StatesTo study the impact of a TP service in reducing hospitalizations and cost savings
Zhong et al (2021) [ ]United StatesTo examine the impact of a TP service compared with in-person across EDs on visit dispositions
Brenner et al (2020) [ ]United StatesTo assess turnaround time with and with no TP and patients’ satisfaction of TP
Freeman et al (2020) [ ]United StatesTo investigate the prevalence of TP use for mental health in general EDs
Kothadia et al (2020) [ ]United StatesTo examine differences in patient disposition for ED psychiatric patients with and with no TP service
Roberge et al (2020) [ ]United StatesTo assess whether TP use for mental health in the ED decreases hospitalization
Fairchild et al (2019) [ ]United StatesTo determine the effects of a TP service on clinical, temporal, and cost outcomes for patients
Saurman et al (2015) [ ]AustraliaTo examine the experience of implementing and using TP for mental health in an ED setting,

b TP: telepsychiatry.

c LOS: length of stay.

d RCT: randomized controlled trial.

Scope and Location of Studies

The 10 studies that examined administrative and clinical outcomes in EDs varied in terms of the research population, study scope, and location. Three of the studies were conducted nationwide in the United States [ 19 , 37 , 38 ], 3 statewide (2 in North Carolina and 1 in New York) [ 15 , 39 , 40 ], and 4 regional in 1 or several local EDs [ 41 - 43 , 45 ]. Of the 10 studies, 3 provided TP services only in rural or remote areas [ 39 , 40 , 43 ], 3 in urban areas [ 41 , 42 , 45 ], and 4 in a mix of urban and rural areas [ 15 , 19 , 37 , 38 ]. Of the 4 studies with rural and urban EDs, 2 reported that most of the TP use occurred in urban areas [ 15 , 19 ] and 2 in rural areas [ 37 , 38 ]. It is worth noting that none of the included studies focused primarily on a comparison between the use of TP in rural and urban areas.

On-site Psychiatric Services and TP Services

Some papers reported whether the medical centers using TP in fact had on-site psychiatric services some of the time, as opposed to having none at all. Three studies reported that less than 20% of their study sites lacked on-site psychiatric service [ 15 , 37 , 38 ], while 1 study reported that 65% of their study sites lacked on-site psychiatric service [ 19 ], and only 1 study reported that all EDs included in their sample lacked on-site psychiatric services [ 41 ]. In addition, TP was reported to be the only form of emergency psychiatric services for more than half of the EDs that participated in 2 nationwide studies in the United States in 2017 and 2019 [ 37 , 38 ].

Effect of TP on Waiting Times in EDs

Two studies examined the effect of TP on waiting time from ED arrival until psychiatric assessment [ 41 , 43 ], while 4 examined the impact on ED LOS from arrival to discharge or admission [ 19 , 37 , 38 , 43 ]. Both studies that examined waiting time for psychiatric evaluation found it significantly lower for TP evaluation compared with in-person [ 41 , 43 ]. Of the 4 studies that examined total ED LOS, 2 showed a significant prolonged ED LOS for TP compared with in-person visits [ 19 , 43 ]; the other 2 studies showed similar prevalence in ED LOS for the same EDs in 2017 and in 2019 [ 37 , 38 ].

Effect of TP on Discharge, Admission, and Transfer to Another Facility

Six studies examined the impact of TP on discharge, admission, and transfer to another facility. Three studies found that TP was associated with significantly lower admission rates compared with in-person visits [ 19 , 40 , 43 ];1 study showed no significant differences in admission rates between TP and in-person evaluation (55% vs 63%; P =.06) [ 42 ]; and 1 study found that EDs that used TP had significantly more admissions than EDs without this service (14% vs 12%; P< .001) [ 15 ]. One study examined whether TP had an impact on the rate of transfers to another facility. The findings were nuanced; total rates of transfer were lower, but among patients with a LOS of 1-2 days the rate of transfer was higher than with in-person care [ 40 ]. Another study that examined patients’ transfer to another facility did not find significant differences between TP patients (31%) compared with in-person (24%) [ 43 ].

Several studies reported on the costs involved with TP. Saeed and colleagues [ 39 ] had examined the cost impact of 19,383 TP visits to 30 EDs in North Carolina. Seventy percent of the visits were encounters for involuntary commitments, and of these, 34% were converted to voluntary hospitalizations sometime before the end of the hospital stay, through a TP encounter. The aggregate cost savings for these conversions of involuntary to voluntary hospitalizations were more than US $20 million [ 39 ].

A national study in 22 US EDs found a significant increase in admissions for TP visits compared with in-person visits, which resulted with a significant increase in spending in a 90-day follow-up analysis [ 19 ]. Another study examined 3 diagnosis groups and found that the significantly most expensive TP visits were for substance abuse cases (US $4556), followed by suicide and self-harm cases (US $3559), and anxiety, mood, and other health disorders case (US $3355) [ 43 ].

Data on Involuntary Commitment Cases

We found limited evidence regarding evaluations for involuntary commitment via TP. As mentioned earlier, Saeed et al [ 39 ] examined cost impact of using TP to enable staff to convert involuntary commitments into voluntary hospitalizations. In another study focused on examining the accuracy of TP compared with in-person evaluations, Bistre et al [ 45 ] evaluated the reliability of TP assessments compared with in-person assessments for involuntary admissions. An interrater agreement on recommended disposition and on indication for involuntary admission between raters was high [ 45 ]. Psychiatrists’ perceived certainty rates were high for both TP and in-person evaluations. Participants reported a high level of satisfaction with both TP and in-person evaluations, which were not significantly different [ 45 ]. In a separate study, patients reported that they were highly satisfied with TP use in the ED, although it was not used to evaluate for involuntary commitment [ 41 ].

Special Behavioral Diagnostic Groups

Some studies have at least implied that TP may not be suitable for some groups of patients that require special attention. A study conducted in the United States found that TP was associated with a reduced wait time until psychiatric assessment, but a longer total ED LOS, compared with usual care. Interestingly, 36% (102/287) of the participants in the TP group were diagnosed as suicide and self-harm, compared with 22% (34/153) in the control group. This study also reported that the time from the end of TP assessment to disposition or discharge was significantly longer for patients with suicide and self-harm than for patients who were diagnosed with anxiety, mood, and other mental health disorders [ 43 ]. Those findings are implying that the poor TP performance may be related to the enlarged diagnosis group that requires more observation in the ED and not a result of TP use. In a national study that included patients with different diagnosis, TP was associated with longer ED LOS, more admissions, and greater costs. Yet, a nonsignificant higher rate of suicide and self-harm cases was found in the TP group (4925/35,861, 14%) compared with the in-person group (3734/34,982, 11%), suggesting, again, that the results may be affected by differences in patient characteristics between the TP group and the control group [ 19 ].

Having examined the existing evidence for TP’s impact on administrative and clinical outcomes in EDs, we will now move to the second research question. In the following section, we will describe the current evidence about the barriers and facilitators to implementing TP in these settings, understanding that successful implementation hinges on navigating these elements.

Second research question: what are the known barriers and facilitators to implementing TP in ED setting?

Our second research question revolves around the implementation process for TP in the ED setting. We found only 1 such study, which was conducted in a rural region of Australia, where the TP service was the main psychiatric service available [ 44 ]. The study was organized around the 6 concepts of the theory of access [ 46 ]. The following are the key findings, organized by these 6 concepts: (1) Accessibility : the staff were able to access mental health specialists for immediate assistance without transferring patients to another facility; (2) Availability : the service was valued as an available resource and eased the demands placed upon staff during emergency mental health presentations; (3) Acceptability : the service was acceptable to the providers and was a constant and easy resource; (4) Affordability : there were no direct costs borne by the providers or the hospitals to use TP to involve a psychiatrist, and it was free for the patients; (5) Adequacy : the 24-hour structure of the program was adequate to the clinical needs, particularly after-hours and on weekends; (6) Awareness : other than 1 provider, everyone else was aware of the service and had some experience using it [ 44 ]. In addition, the service provided a sense of security to the providers. They reported that before the service started, they had felt alone, unsupported, and lacking confidence when dealing with emergency mental health presentations [ 44 ]. All these improved due to the arrival of TP.

Principal Findings

We performed a scoping review to examine the literature regarding the use of TP for adult emergencies. We summarized the evidence regarding (1) administrative and clinical outcomes for patients; and (2) process outcomes of implementing the TP service. Although TP is a known method for psychiatric evaluation, treatment, and follow-up, we found only 11 studies over the past decade to evaluate its application to the ED setting. Ten of these studies evaluated administrative and clinical outcomes, and only 1 study evaluated the implementation process.

Our review included articles that evaluated TP use in various settings and contexts. TP was acceptable and feasible nationally in the United States [ 15 , 19 , 37 , 38 ] and in a study of 7 Australian provinces [ 44 ]. We also found that TP was used in urban areas [ 41 , 42 , 45 ] and rural areas [ 40 , 47 ]. In some cases, TP was used in EDs as the only psychiatric service available [ 41 ]. The 1 study we found about the implementation process reported that TP was accepted and mostly appreciated by the ED staff, especially due to the lack of psychiatric expertise in their setting [ 44 ]. TP was also used for different sorts of patients, including those with anxiety and mood disorders and those with suicide or self-harm [ 43 , 45 ]. The identified lack of evidence regarding the use of TP in EDs significantly impacts our analysis, underscoring a crucial area where further research is needed to draw comprehensive conclusions. This gap highlights the limitations in our current understanding and emphasizes the necessity for targeted studies to elucidate the efficacy and implementation of TP in ED settings. Despite the limited number of studies we found, this diversity of settings and uses somewhat strengthens the argument that TP is broadly applicable across different ED settings and different patient groups.

Waiting Times

On the issue of ED waiting times, the existing evidence is mixed. Two studies showed that the ED waiting time from patients’ arrival until psychiatric evaluation was significantly lower for TP visits than for in-person visits [ 41 , 43 ]. However, 2 studies found that the total ED LOS was significantly longer for TP visits than for in-person visits [ 19 , 43 ]. Unfortunately, none of the included studies examined waiting times from the psychiatric evaluation until admission or discharge for TP compared with in-person visits, so this remains an unexamined issue. However, because TP is shortening waiting times for initial psychiatric assessment, this may contribute to putting the patient on a better path from the beginning [ 29 ]. This is supported by the main finding of this review that TP reduced admission rates [ 19 , 40 , 42 , 43 ]. In other words, perhaps the fast psychiatric evaluation by TP resulted in expert psychiatric input to the case sooner, which may partly explain the lower admission rate. Further studies will help clarify these points.

Patients’ Characteristics

Another factor that remains relatively unexamined is whether TP is equally applicable to different sorts of patients. Most enrolled studies did not examine TP use through different patient characteristics, such as diagnosis groups or the need for direct observation. Patients who require direct observation usually have more severe presentations and thus a longer LOS [ 48 ]. Two studies did focus on the use of TP for patients seen for self-harm and suicide; these studies showed higher ED LOS [ 19 , 43 ]. Therefore, there is a need for further studies of patients with these more severe presentations to ensure that TP is applicable to them as well.

Lack of Findings Regarding Patients Evaluated for Involuntary Commitment

Patients requiring evaluation for involuntary commitment are a distinct group. As presented in the Results section, in 1 study, staff used TP to help evaluate which patients had improved enough to have their involuntary commitments converted into voluntary hospitalizations [ 39 ]. However, this does not speak to the initial decision to pursue an involuntary commitment. Given our group’s experience, it may be easy to understand why relatively few studies have evaluated the use of TP for patients evaluated for involuntary commitment. Our ongoing study of this issue required special permission from the Israeli Ministry of Health after consultation with the Ministry of Justice and the Union of Psychiatrists [ 49 ]. Thus, it is easy to see why there have been relatively few studies regarding the use of TP for this special use case and certainly more are needed.

Patient Transfer

Another issue that was examined was the impact on interhospital transfers. One study found that the use of TP increased the number of transfers [ 43 ]. On the other hand, another study showed that among patients with an extended LOS, significantly less TP patients (29%) were transferred to a psychiatric hospital compared with in-person patients [ 40 ]. These divergent results may point to a complex and nuanced effect of TP on doctor-patient relationship. Technology in medicine holds the promise to contribute a more personalized style of care [ 50 ]. However, remote communication between psychiatrists and patients may affect doctor-patient engagement and lack personal touch compared with in-person encounters [ 51 ]. There is a possibility that it is easier for the psychiatrist using TP in emergency cases to decide on transfer rather than admission to the present facility. If there is an association between TP use in the ED and more patient transfers, this could lead to inconvenience for family members, as well as the cost of transport [ 52 ]. The impact of TP on the rate of interfacility transfers also requires further study.

Rural and Urban Areas

TP is perceived often as a critical solution for the lack of mental health services in rural and remote areas [ 31 , 53 ]. However, findings from this review indicate that TP is used in urban areas as well [ 41 , 42 ]. Several studies showed that TP was even more common at urban settings [ 15 , 19 ], even when they have existing on-site psychiatric services [ 15 ]. The demand to use TP even in urban areas may be driven by the fact that the attending physician is at home for more hours than not, and must drive to the hospital. However, rural areas may face special issues with TP use, including inadequate technology literacy [ 2 ], bad internet connectivity [ 54 ], or a general lack of resources [ 2 , 55 ]. Despite these challenges, there is a strong incentive to use TP in rural areas, so it may be worth the effort of addressing the challenges.

Strengths and Limitations

This scoping review had several strengths and limitations. A broad range of the main databases were searched, which allowed a comprehensive search. This review provides robust evidence of the included studies, provides a deeper understanding of the current evidence, and provides the needed data to broaden our understanding of TP in emergency settings.

This review also has some limitations. We examined only those studies published in English. All studies that we found were conducted in developed countries, which provides a limited perspective. In addition, the data we found about the use of TP for evaluations regarding possible involuntary commitment were particularly limited. This will be a key area for future research. We also did not find any studies that specifically compared TP use in urban versus rural settings, or that compared its use for specific groups of patients (eg, by diagnosis). Furthermore, we found only 1 interventional study; the others were observational. However, all our included studies had sample sizes larger than 30 participants and a detailed description of the study methodology. In part, we chose to do a scoping review as opposed to a systematic review, because the available literature was so limited.

Conclusions

TP has a strong evidence base for general use and is known to be acceptable, reliable, and effective. However, only a very few studies in the past decade (11 studies) evaluated its use in the ED. While these studies generally supported the idea that TP was feasible and highly acceptable, it is clear that further studies are needed. Further studies are needed for examining TP evaluations for involuntary commitments in the ED setting. In addition, there is a need for studies on the extent and trends of TP usage over time, including in the context of COVID-19. We also need more comprehensive assessments comparing the effectiveness of TP evaluations with in-person assessments and implementation science research to better understand the barriers, facilitators, and opportunities for adopting this practice in EDs. Special attention should be given to rural areas, which usually have limited access to mental health services and yet may face special challenges in implementing them.

Acknowledgments

The authors would like to thank Tomer Ben-Shushan from the Berman Medical Library, Hebrew University, for conducting the database search for the paper.

Authors' Contributions

LS initiated the study and drafted the manuscript. LS and AJR led the scoping review, design, and analysis. All authors (LS, RE, and AJR) discussed the results, reviewed, and approved the final version of the manuscript.

Conflicts of Interest

None declared.

PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist.

Web-based search strategy conducted on April 24, 2023.

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Abbreviations

emergency department
length of stay
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews
telepsychiatry

Edited by T de Azevedo Cardoso; submitted 13.08.23; peer-reviewed by P Yellowlees, E Eboreime; comments to author 22.02.24; revised version received 25.02.24; accepted 29.04.24; published 15.07.24.

©Ligat Shalev, Renana Eitan, Adam J Rose. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 15.07.2024.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.

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Characteristics of Melatonin Use Among US Children and Adolescents

  • 1 Department of Integrative Physiology, University of Colorado Boulder, Boulder
  • 2 Department of Public Health, Purdue University, West Lafayette, Indiana
  • 3 Sleep Health and Wellness Center, Santa Barbara, California
  • 4 Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island

In a 2017-2018 study, 1 1.3% of US parents reported that their children consumed melatonin in the past 30 days, and sales more than doubled between 2017 and 2020. 2 In the US, melatonin is considered a dietary supplement, is not regulated by the US Food and Drug Administration, and requires no prescription, raising particular concern because the amount of melatonin present in over-the-counter supplements can vary drastically. In a recent examination of 25 commercial supplements, actual melatonin quantity ranged from 74% to 347% of the labeled content. 3 Additionally, incidence of melatonin ingestion reported to poison control centers increased 530% from 2012 to 2021, 4 largely occurring among children younger than 5 years. Current data are lacking on the prevalence of melatonin use and the frequency, dosing, and timing of melatonin administration in US youth.

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Hartstein LE , Garrison MM , Lewin D , Boergers J , LeBourgeois MK. Characteristics of Melatonin Use Among US Children and Adolescents. JAMA Pediatr. 2024;178(1):91–93. doi:10.1001/jamapediatrics.2023.4749

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    INTRODUCTION. We previously estimated that about 660,000 (42% of all) incident cancer cases and 265,000 (45% of all) cancer deaths in the United States in 2014 were attributable to potentially modifiable risk factors. 1 However, information on risk factors associated with specific cancer types and the magnitude of associations may evolve over time and since the publication of our previous ...

  21. International Journal of Research Publications

    Welcome To IJRP. International Journal of Research Publications (IJRP) is having ISSN (2708-3578) (online), and DOI: 10.47119/27083578, bimonthly international journal, being published since the year 2017. IJRP is an active member of Crossref and all published papers are issued DOI number.. International Journal of Research Publications (IJRP) is a quality publication of peer-reviewed and ...

  22. International Journal of Research

    The International Journal of Research (IJR), with ISSN 2348-6848 for its online edition and 2348-795X for its print edition, stands as a global, peer-reviewed, and open-access journal published monthly.IJR is at the forefront of a paradigm shift in scholarly publishing, championing a liberal, open-access model with swift, high-quality peer review processes.

  23. Journal Citation Reports

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  24. International Journal of Research and Review

    International Journal of Research and Review (P-ISSN: 2454-2237; E-ISSN: 2349-9788;)is an Indexed, double-blind, peer-reviewed, open access international journal dedicated to promotion of research in multidisciplinary areas. ... The journal publishes papers based on original research that are judged by critical reviews, to make a substantial ...

  25. Neural Representations of Sensory Uncertainty and Confidence are

    The research described in this paper was supported by the National Institute of Mental Health as part of the National Research Service Award (Grant #:1F31MH125589), and the Zuckerman Institute MR Seed Grant Award (Grant #: CU-ZI-MR-S-0017) both awarded to Michael Cohanpour. ... Journal of Neuroscience 5 July 2024, e0974232024; DOI: 10.1523 ...

  26. Call for papers: Thriving during turbulent times: The role of

    A call for papers from the APA journal Consulting Psychology Journal for a special issue that aims to bridge the gap between academic research and practical application by exploring innovative, science-based practices for building change capability.

  27. Journal of Engineering Research

    Journal of Engineering Research (JER) is an international, peer reviewed journal which publishes full length original research papers, reviews and case studies related to all areas of Engineering such as: Civil, Mechanical, Industrial, Electrical, Computer, Chemical, Petroleum, Aerospace, Architectural, etc. JER is intended to serve a wide range of educationists, scientists, specialists ...

  28. Journal of Medical Internet Research

    Ten papers reported on administrative and clinical outcomes of TP use in the ED setting and 1 on the barriers and facilitators of its implementation. TP is used in urban and rural areas and for settings with and with no on-site psychiatric services. ... Journal of Medical Internet Research 8499 articles JMIR Research Protocols 4054 articles ...

  29. Full article: Does School Academic Selectivity Pay Off? The Education

    ABSTRACT. The long-term benefits of academically selective schools have not been thoroughly explored in the Australian context. This research draws on data from a longitudinal study of Australian young people (n = 2933) and utilises Nearest-neighbour matching techniques to explore whether individuals who attend academically selective schools have better outcomes than those who attend non ...

  30. Characteristics of Melatonin Use Among Children and Adolescents

    In a 2017-2018 study, 1 1.3% of US parents reported that their children consumed melatonin in the past 30 days, and sales more than doubled between 2017 and 2020. 2 In the US, melatonin is considered a dietary supplement, is not regulated by the US Food and Drug Administration, and requires no prescription, raising particular concern because the amount of melatonin present in over-the-counter ...