Biology Research Projects for High School Students: 20 Ideas To Try This Summer

Photo of Janos Perczel

By János Perczel

Co-founder of Polygence, PhD from MIT

15 minute read

biology research project

Biology and biomedical research are two of the most popular academic disciplines among high schoolers. If you’re someone who’s interested in those fields and you’re looking for research opportunities this summer, you’ve come to the right place! With the study of biology, not only can you gain a better understanding of the natural world, but your research can have practical applications in fields like medicine, agriculture, and environmental science. Whether you’re just starting out in your exploration of biology, have taken a biology class in school, or you’re looking to do some advanced research to submit to your state’s science fair, we have level-appropriate ideas for you!

With a variety of topics like cancer treatment, genetics, neurodegenerative diseases, and marine life, we’ve got you covered. Here is a curated list of 20 different research project ideas to get those creative juices flowing. If you’re hungry for more, head over to our comprehensive Project Ideas database here and browse over 2800 more ideas!  

Research YOUR fave areas of Biology and Medicine

Polygence pairs you with an expert mentor in to create a passion project around biology and medicine. Together, you work to create a high quality research project that is uniquely your own. We also offer options to explore multiple topics, or to showcase your final product!

biology project ideas for high school

Human Body Project Ideas

Rate of cognitive decline in different elevations.

Oxygen partial pressure decreases with altitude, challenging blood oxygenation which may affect brain function. If you’ve ever felt some altitude sickness, then this is exactly what’s happening. This is because the atmospheric pressure decreases at higher elevations, leading to a decrease in the partial pressures of the gasses in the air, including oxygen. And of course, oxygen is needed for us to function. What is the effect on brain health/ cognition in sudden increased elevation: say, climbing Mount Everest? Does chronic exposure to high elevations increase the likelihood of dementia? In this project, a meta-analysis of published works examining the effects of altitude on cognition would be conducted.

Idea by mentor Alyssa

Building a Blood Vessel

Use online graphics to illustrate how a blood vessel forms. Blood vessels are structures that carry blood and are responsible for transporting nutrients and oxygen throughout the body. There are three main types of blood vessels: arteries, veins, and capillaries. For this project, complete a literature search to understand what is known about blood vessel growth. Then, utilize this information to generate a graphic with no words to demonstrate how the vasculature (network of blood vessels) forms. The goal of this project is to explain science without using text and therefore make it more available to a larger community.

Idea by mentor Natalie

Examining the bacterial profile of various households

As of late, bacterial microbiomes have been a huge and interesting topic in the field of bacteriology as they play an important role in human health. Bacterial microbiomes are communities of bacteria that live on or outside organisms. They’re found in various parts of the human body, and help us to digest food and regulate our immune system. In this project, you will seek to understand how skin microbiomes can differ between different  individuals of different households. This project will require making different bacterial media that can be made at home selecting for various microorganisms. If you’re new to preparing bacterial media, check out this resource here!

Idea by mentor Hamilton

Regulation of Circadian Clocks

Sleep is known to be governed by two distinct processes: a circadian clock that aligns sleep and wakefulness to the solar day and the sleep homeostat that encodes for sleep debt as a compensatory mechanism against sleep loss. You’ve most likely heard about circadian rhythm and our body’s internal clock, and circadian regulation of sleep is a fundamental process that allows animals to anticipate sleepiness or wakefulness consistently every day. These mechanisms can be regulated in multiple ways: at the gene, protein, gene, and clock neuronal level. In this project, we will focus on 1) how to efficiently digest primary and review articles to compile and condense information, 2) investigate how circadian clocks are regulated at these different genetic levels, and 3) try to effectively summarize the information we've gathered. We can present this information in a variety of ways, and what the final product looks like is up to you.

Idea by mentor Oscar

The Biology of Aging

Aging is the number one risk factor for a variety of diseases including cancer, neurodegenerative disease, and loss of hearing/sight. We are only now beginning to truly understand the process of aging and have even started to uncover ways that we could stop, or potentially reverse, the effects of aging. What are the hallmarks/signs of aging? How do researchers study 'aging'? How does human lifespan and aging compare to the rest of the animal kingdom? Is it possible to stop or reverse the effects of aging? What advancements are being made related to this? We could explore these questions or brainstorm others you might have about the biology of aging.

Idea by mentor Emily

Animals, Plants, and Nature Project Ideas

How genetically engineered mosquitoes are reducing rates of vector-borne diseases such as zika.

Many countries are already releasing millions of genetically engineered mosquitoes into the wild every week. These mosquitoes have been modified to reduce their ability to transmit disease-causing pathogens like dengue fever, Zika, and malaria, and are sent into the wild to mate with disease-carrying mosquitoes. However, this is still controversial as some people are concerned about the unintended consequences on the environment. What could be the potential pros and cons for this? The project will mainly focus on doing meta analysis of articles and watching informative videos to understand how/why genetically engineered mosquitoes can be used to reduce rates of different diseases. Students will have the chance to use critical thinking and do in-depth research on genetic engineering techniques, how scientists determine breeding rates and number of insects released, and epidemiology of different bloodborne diseases.

Idea by mentor Vanessa

Efficacy of Marine Protected Areas

Marine protected areas (MPAs) are areas of ocean or coastal waters that are set aside for the conservation and sustainable use of marine resources. These areas are established by governments, NGOs, or other organizations, and they can take different forms, from fully protected "no-take" zones to areas with regulated fishing or other activities. Marine protected areas have the potential to guide sustainable resource management and protect biodiversity, but have a host of reasons for why they are not currently effective. Explore reasons for why MPAs may not be effective. Then develop a framework for mapping, modeling, and implementing an effective Marine Protected Area.

Bioinspiration: Do animals hold the answers?

Can the toxins produced by frogs help us fight antibiotic resistant bacteria strains? How can understanding how lizards and newts regrow their limbs help us improve wound treatment? Why do tilapia skins help with burns? Discover the role of animals in the development of modern medicine as well as its potential. Are there any ethical concerns with these developments and findings? If so, what are they and do they matter? Share your findings in a research proposal, article, or presentation.

Idea by mentor Cheyenne

How Climate Change Can Affect Future Distributions of Rare Species

Climate change, such as global warming and longer drought, can threaten the existence of some of the rarest plants on earth. It is important to understand how future suitable habitats will change for these rare species so that we can target our conservation efforts in specific areas. In this project, you will identify a rare species that you like (it can be animals, plants, or fungi!), and gather the data online on its current occurrences. Then you will learn how to perform species distribution modeling to map its current and future suitable habitat areas. To get you started on learning species distribution modeling, check out this Youtube resource here. The changes in the amount or location of future suitable habitats can significantly affect the destiny of a rare species. By doing this project, you will not only learn skills in data analyses but also become the best ambassador for this rare species that you love. 

Idea by mentor Yingtong

A Reef’s Best Frenemies

Coral reefs are in global decline. A primary cause of this is "coral bleaching" which results in the white reefs we often see in the news. Coral bleaching is actually the breakdown in the partnership between the coral animal and tiny, symbiotic algae that live within its cells. Corals and algae have a variety of thermal tolerances which are likely decided by genetic and environmental factors. However, despite how important this relationship is, it's currently very poorly understood. This project would review existing literature on the symbiotic partnernship and try to identify factors that predict bleaching and thermal resilience.

Idea by mentor Carly

Dive in to BioMed NOW!

Register to get paired with one of our expert mentors and to get started on exploring your passions today! You have agency in setting up your schedule for this research. Dive in now!

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Diseases and Treatments Project Ideas

The understanding of a new and upcoming treatment: immunotherapy.

Immunotherapies have been growing in the past few years as alternative treatments for many types of cancer. These treatments work by boosting the patient's immune system to fight the disease, however it is not always effective. There are many types of immunotherapies with various nuances, but they all work to attack specific cells that are causing the disease. For this project, pick one of a few types of immunotherapy and deeply understand the mechanism of action and what is the current effectiveness against the cancer it treats.

Idea by mentor Hannah

Exploring The Cancer Genome Atlas data 

There has been an explosion of publicly available data for cancer. The Cancer Genome Atlas was a research program with the purpose of creating a comprehensive catalog of genomic and molecular information about different types of cancer, with the aim of improving our understanding of the disease and developing new treatments. The dataset has been used to identify new cancer subtypes, develop diagnostic tests, and discover potential targets for new cancer therapies. Explore the implications and impact of The Cancer Genome Atlas data, and why it’s become so important.

Idea by mentor Hersh

Systematic Review and Meta-Analysis of Physiological Benefits of Fasting-induced Autophagy

Autophagy, meaning "self-eating", is a cellular process where damaged or unwanted components are disposed. Autophagy has been linked to various diseased pathologies, including cancer and heart disease. Fasting or specific dietary lifestyles may induce levels of autophagy in the human body. In this project, we will perform and systematic review and meta-analysis of fasting or diet-induced autophagy and its benefits on the body. You will gain skills in 1) searching and reviewing primary literature, 2) computational skills for performing data analysis (R language), and 3) writing your scientific findings.

Idea by mentor Jose 

The Amyloid Hypothesis: Sifting through the controversy

For many years, scientists have thought that amyloid beta was the protein responsible for a patient developing Alzheimer's Disease symptoms. This "Amyloid Hypothesis" is now being questioned in light of current clinical data. Recently, drugs have been developed that reduce amyloid beta in patients. Surprisingly, the drugs worked in reducing amyloid beta, but it did not result in the slowing of disease pathology. Does this mean that the amyloid hypothesis is incorrect? Is amyloid beta less important in the progression of disease then what we once thought? This research project aims to explore the issues with the amyloid hypothesis and to assess where we stand in our understanding of amyloid beta's contribution to Alzheimer’s.

Idea by mentor Patrick

How do vaccines work?

During the COVID pandemic, vaccines have been all over the news! But how do they actually work? What’s the science behind them? Through this project, you will explore how vaccines work and the history of science behind vaccine development. While the final product of the projectwill be up to you, the ultimate goal of this project is for you to be a true public health advocate for vaccines and to be able to communicate why vaccines are so important in a way that the general public can understand.

Idea by mentor Helen

Sleep Disruption Profiles in Various Mouse Models of Alzheimer’s

Alzheimer's disease (AD) has been studied for decades but we are no closer to understanding the mechanisms of the disease. Because of the vast number of researchers studying AD, there are numerous models used to study the disease. All these models have different sleep profiles, phenotypes, disease onsets, sex differences etc. Therefore, in this project we will compile a document based on extensive literature review about the various models there are. We will focus on sleep profiles in these animals with an emphasis on male and female differences. This information is valuable because it is important to know which model is best to use to answer your scientific questions and there is a lot of criticism (by other scientists) that can be brought on by the model chosen so you need to be able to justify your choice. This project will also introduce you to the world of AD research and some of the gaps in knowledge in the field.

Idea by mentor Shenee

Rethinking The Treatment Of Neurodegenerative Diseases

Neurodegenerative diseases affect millions of people worldwide. They are conditions that affect the nervous system, particularly the brain and spinal cord, and examples include Alzheimer’s and Parkinson’s. While billions of dollars have been spent trying to find treatments for the disease, very few drugs and therapies have had a meaningful impact on slowing down disease progression. This is often because by the time someone is diagnosed with a disease, it has progressed too far for a treatment to have a substantial effect. Some recent approaches to treatment have turned to looking for early indications of the disease (termed "biomarkers") that can occur before the onset of symptoms. By diagnosing disease and beginning treatment before symptoms arise, these treatments could have a more profound effect in slowing down the progression of disease. Students could review the recent progress being made on identifying biomarkers for neurodegenerative diseases, and either write a paper or even record a podcast on their findings!

Idea by mentor David

Genetics Project Ideas

Height and genetics: nature or nurture.

How much do your genes determine your height? How much do nutrition and environmental factors play a role? What gene variants are implicated in height differences and what is the role of epigenetics? Epigenetics is the study of heritable changes in gene expression or cellular phenotype that occur without changes to the underlying DNA sequence. These changes can be influenced by diet and lifestyle. We will access and analyze an open dataset on twins to estimate the correlation between monozygotic twins (who have the exact same DNA) and height. You will learn to use R to open a dataset, analyze data with statistical methods such the student’s t-test, and display your data as graphs and charts. Finally, you will learn how to make a research presentation on height and genetics, describe the research methods, and present the data in a compelling and thorough way.

Idea by mentor Adeoluwa

The World of Personalized Medicine

Similar to our fingerprints, our genetic code is also unique to each individual person. Our genetic code is what determines our hair color, height, eye color, skin tone...just about everything! For those that develop diseases such as cancer, their genetic code found inside the malignant cells that comprise a tumor may also be unique to them or to certain groups of people with similar mutations (the drivers of disease). So why is it that we treat each person the same way even though the genetic drivers of that disease may be disparate? The world of Personalized Medicine is new and exciting and looks to circumvent this problem. Personalized Medicine (also known as precision medicine) uses the genetic code of a patients disease to guide treatment options that prove to be highly efficacious. Together, lets write a review on a disease of your choice that could benefit from Personalized Medicine based on current literature and research.

Idea by mentor Somer

General Biology Project Ideas

Teach a biology concept two ways: to your fellow students and to the general public.

One of the best ways to learn is to teach. Choose a biological concept that interests you and prepare a lesson and or demo on it. The format should be a video recording of yourself teaching (a la Khan Academy or a Zoom class), but the other details are up to you. Consider incorporating a demonstration (e.g. how can you use items from your kitchen to illustrate properties of mixtures?) or animation (e.g. to illustrate molecular motion). Also consider how you will check that your students understand the concept(s) and/or skill(s) you have taught them. Prepare and record two versions of your lesson: one intended for your peers and one for the general public. How will the versions differ to reflect these different audiences? You will learn what it's like to teach, gain a much greater understanding of your chosen concept(s)/skill(s), and learn how to communicate science to different audiences.

Idea by mentor Alexa

Once you’ve picked a project idea, check out some of our resources to help you progress with your project! Whether you’re stuck on how to cite sources , how to come up with a great thesis statement , or how to showcase your work once it’s finished , we’ve created blog posts to help you out. If you’re interested in doing one of the biology research projects with the help of an amazing mentor at Polygence, apply now ! If you would like some help with coming up with your own idea, book a complimentary consultation call with our admissions team here !

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biology project ideas for high school

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107+ Best Biology Project Ideas For High School Students

Biology Project Ideas

Biology is a captivating and interesting field. through biology, students study about life and its processes. If you are a biology student and looking for the best biology project ideas, then we are here to give you all the topics that make your overall journey most interesting. 

You can easily learn biology with here given project ideas. Basically, engaging in biology projects not only improves your understanding of the subject but also lets you study miscellaneous elements of life sciences. 

Whether you’re a student searching for a magnetic science fair project or a biology fanatic desiring to delve more in-depth into the subject, this blog post will give you with most creative and exciting biology project ideas.

What is Biology

Simply said, biology is the study of life.

Biologists now agree that life is a product of a certain set of processes that arise from the arrangement of matter. 

Biologists have compiled a list of features that define the “set of life processes” shared by all organisms as living:  The living:

  • Use up stuff and power.
  • To have offspring; to perpetuate one’s genes.
  • Evolve and expand.
  • Demonstrate inherited differences or variants.
  • Are well-suited to their natural habitat.
  • React to external influences.

The scientific nature of biology has led to the categorization of life’s defining features into the following categories:

  • Harmony and Variety
  • Constancy in Genealogy
  • Characteristics of Human Nature
  • Harmony between Form and Operation
  • Organism-Environment Interactions

All of the Life Science classes have a common thread of these key ideas.

Top 11+ Biology Project Ideas For Students

Have a close look at some of the best biology project ideas.

Biology Project Ideas #1:- Investigating Genetic Variation

biology project ideas for high school

Explore this fascinating topic by studying the genetic variation in a particular population or comparing the genomes of different organisms.

Biology Project Ideas #2:- Exploring Ecosystem Dynamics

biology project ideas for high school

Ecosystems are complex systems consisting of various organisms and their physical environment. Choose an ecosystem of interest and study its dynamics.

You can investigate the interrelationships between different species, analyze the energy flow and nutrient cycling, or examine the effects of human activities on ecosystem stability.

Biology Project Ideas #3:- Unveiling the Microbial World

biology project ideas for high school

Focus your project on studying a specific group of microbes, such as bacteria or fungi.

You can explore their diversity, ecological functions, or their potential applications in fields like biotechnology or medicine.

Biology Project Ideas #4:- Examining Human Anatomy and Physiology

biology project ideas for high school

Choose a specific system or organ and investigate its structure, function, and interactions with other systems. You can explore topics like the cardiovascular system, nervous system, or respiratory system.

Biology Project Ideas #5:- Investigating Plant Growth and Development

biology project ideas for high school

Changes in gene expression in response to environmental variables like climate change are only one example of what scientists studying plant growth and development look for.

Biology Project Ideas #6:- Understanding the Impact of Environmental Factors

biology project ideas for high school

Environmental factors greatly influence the distribution and behavior of organisms.

You can investigate how different species respond to these factors and explore their adaptive mechanisms.

Biology Project Ideas #7:- Studying Animal Behavior and Adaptation

biology project ideas for high school

Focus your project on studying a particular animal species or group and investigate their behavior patterns, mating strategies, or adaptations to their environment.

You can conduct field observations, and experiments, or analyze existing data.

Biology Project Ideas #8:- Investigating Cellular Processes

biology project ideas for high school

Choose a cellular process, such as mitosis, meiosis, or cellular respiration, and explore its mechanisms and regulation.

You can use microscopy techniques, genetic analysis, or biochemical assays to investigate these processes.

Biology Project Ideas #9:- Exploring the Effects of Drugs on the Human Body

biology project ideas for high school

Choose a specific drug or class of drugs and study their impact on physiological processes.

Effects of caffeine on heart rate, the impact of recreational drugs on the brain, and the mechanism of action of painkillers, you can explore easily.

Biology Project Ideas #10:- Unraveling the Mysteries of DNA

biology project ideas for high school

Dive into the world of DNA by studying its structure, replication, or role in inheritance.

You can conduct experiments like DNA extraction, PCR amplification, or DNA sequencing to explore various aspects of this fascinating molecule.

Biology Project Ideas #11:- Investigating the Role of Enzymes in Biological Reactions

biology project ideas for high school

Focus your project on studying a specific enzyme or group of enzymes and investigate their function, regulation, or industrial applications.

You can design experiments to measure enzyme activity, optimize reaction conditions, or explore enzyme inhibition.

Biology Project Ideas #12:- Exploring the Diversity of Fungi

biology project ideas for high school

Fungi represent a diverse group of organisms with unique characteristics and ecological roles. Choose a specific group of fungi, such as mushrooms or yeasts, and study their diversity, life cycle, or ecological interactions.

You can explore topics like fungal diseases, symbiotic relationships, or the use of fungi in bioremediation.

Biology Project Ideas #13:- Understanding the Mechanisms of Photosynthesis

biology project ideas for high school

Photosynthesis is the process by which plants and some other organisms convert light energy into chemical energy.

Investigate the mechanisms of photosynthesis by studying factors that influence its efficiency, such as light intensity, carbon dioxide concentration, or temperature.

You can use techniques like chlorophyll fluorescence or oxygen evolution assays to measure photosynthetic activity.

Here are 107+ best biology project ideas across various categories:

Plant Biology Project Ideas:

  • Investigate the Effect of Different Fertilizers on Plant Growth.
  • Study the Circadian Rhythms in Plants.
  • Explore the Role of Mycorrhizal Fungi in Plant Nutrition.
  • Analyze the Impact of Light Wavelengths on Photosynthesis.
  • Investigate Plant Responses to Gravity (Geotropism).
  • Study the Allelopathic Effects of Plants on Each Other.
  • Examine the Water Absorption Rate in Various Types of Soil.
  • Investigate the Nutrient Uptake in Hydroponic vs. Soil-Grown Plants.
  • Explore the Process of Plant Transpiration.
  • Study the Role of Plant Hormones in Growth and Development.
  • Investigate the Effect of Music on Plant Growth.
  • Analyze the Impact of Temperature on Seed Germination.
  • Study Plant Defense Mechanisms Against Herbivores.
  • Explore the Symbiotic Relationships Between Plants and Pollinators.
  • Investigate the Effects of Air Pollution on Plant Health.

Human Biology Project Ideas:

  • Investigate the Relationship Between Blood Type and Diet.
  • Study the Impact of Stress on Blood Pressure.
  • Analyze the Effect of Exercise on Lung Capacity.
  • Investigate the Genetics of Taste Perception.
  • Study the Human Microbiome and its Impact on Health.
  • Explore the Effect of Sleep on Cognitive Function.
  • Investigate the Link Between Diet and Acne.
  • Study the Effect of Caffeine on Heart Rate.
  • Investigate the Factors Affecting Reaction Time.
  • Explore the Genetics of Eye Color.
  • Study the Impact of Music on Mood and Brain Activity.
  • Investigate the Effect of Different Diets on Weight Loss.
  • Analyze the Factors Influencing the Human Lifespan.
  • Study the Physiology of Exercise-Induced Endorphin Release.
  • Investigate the Relationship Between Blood Sugar Levels and Mood.

Microbiology Projects:

  • Study the Antibacterial Properties of Common Household Items.
  • Investigate the Formation of Biofilms on Various Surfaces.
  • Explore the Effects of Antibiotics on Beneficial Gut Bacteria.
  • Study the Microbial Diversity in Different Ecosystems.
  • Investigate the Role of Microbes in Decomposition.
  • Study the Effects of Temperature on Microbial Growth.
  • Investigate Antibiotic Resistance in Bacterial Strains.
  • Study the Microbiome of Indoor vs. Outdoor Environments.
  • Investigate the Use of Probiotics in Promoting Gut Health.
  • Explore the Fermentation Process in Food Production.
  • Investigate the Microbial Communities in Hydrothermal Vents.
  • Study the Role of Microbes in Soil Nutrient Cycling.
  • Investigate the Antibacterial Properties of Natural Substances.
  • Study Microbial Fuel Cells for Sustainable Energy Production.
  • Investigate the Microbiota in Human Skin Health.

Zoology Projects:

  • Study the Behavior of Ants in Response to Food Types.
  • Investigate the Effects of Light Pollution on Nocturnal Animals.
  • Explore the Camouflage Adaptations of Insects.
  • Study the Migration Patterns of Birds.
  • Investigate the Impact of Noise Pollution on Marine Life.
  • Analyze the Communication in Dolphin Pods.
  • Study the Territorial Behavior of Small Mammals.
  • Investigate the Diet Preferences of Herbivorous vs. Carnivorous Animals.
  • Study the Courtship Rituals of Frogs.
  • Investigate the Effect of Pollution on Amphibian Populations.
  • Analyze the Social Hierarchy in Primate Groups.
  • Study the Impact of Climate Change on Polar Bears.
  • Investigate the Hunting Strategies of Predatory Insects.
  • Study the Nest-Building Behavior of Birds.
  • Investigate the Impact of Urbanization on Bat Populations.

Environmental Biology Project Ideas:

  • Analyze the Water Quality of Local Ponds and Lakes.
  • Investigate the Impact of Pesticides on Honeybee Populations.
  • Study the Effects of Ocean Acidification on Coral Reefs.
  • Analyze the Air Quality in Urban vs. Rural Areas.
  • Investigate the Role of Wetlands in Flood Control.
  • Study the Diversity of Aquatic Macroinvertebrates as Bioindicators.
  • Investigate the Impact of Deforestation on Biodiversity.
  • Study the Erosion Control Potential of Different Plant Species.
  • Investigate the Effect of Oil Spills on Marine Ecosystems.
  • Analyze the Role of Riparian Zones in Water Quality.
  • Study the Succession of Plant Species in Abandoned Fields.
  • Investigate the Ecological Importance of Bees in Pollination.
  • Analyze the Impact of Invasive Species on Native Ecosystems.
  • Investigate the Microbial Decomposition of Organic Waste.
  • Study the Role of Forests in Carbon Sequestration.

Genetics Projects:

  • Study the Inheritance Patterns of Genetic Disorders.
  • Investigate the Genetics of Flower Color in Plants.
  • Analyze the DNA Barcoding of Local Wildlife Species.
  • Investigate Gene Expression in Response to Environmental Stress.
  • Study the Role of Epigenetics in Inheritance.
  • Investigate Genetic Mutations in Cancer Cells.
  • Analyze the Genetic Diversity of Endangered Species.
  • Study the Genetics of Taste Receptors.
  • Investigate Genetic Variation in Human Populations.
  • Study the Genetic Basis of Drug Resistance in Pathogens.
  • Investigate Genetic Engineering Techniques in Agriculture.
  • Analyze the Genetics of Eye Disorders.
  • Study the Inheritance of Behavioral Traits in Animals.
  • Investigate the Genetic Basis of Immune System Disorders.
  • Analyze the Role of Non-Coding RNAs in Gene Regulation.

Ecology Projects:

  • Study the Impact of Urbanization on Local Wildlife.
  • Investigate the Trophic Interactions in a Pond Ecosystem.
  • Analyze the Succession of Plant Communities in a Forest.
  • Study the Impact of Grazing on Grassland Biodiversity.
  • Investigate the Nutrient Cycling in a Freshwater Ecosystem.
  • Analyze the Effect of Temperature on Species Distribution.
  • Study the Ecological Role of Keystone Species.
  • Investigate the Impact of Invasive Plants on Native Flora.
  • Analyze the Food Web in a Marine Ecosystem.
  • Study the Habitat Preferences of Amphibians.
  • Investigate the Effect of Predation on Prey Populations.
  • Analyze the Competition Between Species in an Ecosystem.
  • Study the Impact of Climate Change on Plant-Pollinator Interactions.
  • Investigate the Relationship Between Biodiversity and Ecosystem Stability.
  • Analyze the Effect of Pollution on Stream Ecosystems.

Biochemistry Projects:

  • Study the Enzyme Kinetics of Catalase.
  • Investigate the Chemical Composition of Different Soils.
  • Analyze the Protein Structure and Function.
  • Study the Metabolic Pathways in Cellular Respiration.
  • Investigate the Effect of pH on Enzyme Activity.
  • Analyze the Chemical Composition of Various Foods.
  • Study the Role of Lipids in Cell Membranes

Top 10 Best Biology Project Ideas For College

If you’re looking for biology project ideas for college-level studies, here are some interesting topics to consider:

  • Cancer Cell Biology
  • Neurobiology and Brain Function
  • Biodiversity and Ecosystem Dynamics
  • Evolutionary Genetics
  • Stem Cell Research
  • Ecological Impact of Climate Change
  • Molecular Basis of Diseases
  • Human Microbiome and Health
  • Biotechnology and Genetic Engineering
  • Behavioral Ecology and Animal Communication

10 Best Biology Project For Ideas For Class 12

If you’re in class 12 and seeking biology project ideas, here are some interesting topics to consider:

  • DNA Fingerprinting and Forensics
  • Study of Enzyme Activity
  • Effect of Different Stimulants on Plant Growth
  • Investigating Antibiotic Resistance
  • Investigating the Effects of Pollution on Aquatic Life
  • Human Reproductive System and Fertility
  • Comparative Study of Blood Groups
  • Plant Hormones and Growth Regulation
  • Study of Mendelian and Non-Mendelian Genetics
  • Investigation of Photosynthesis in Different Light Conditions

7+ Simple And Easy Biology Project For Ideas For Class 10

If you’re in class 10 and seeking biology project ideas, here are some interesting topics to consider:

  • Effects of pH on Enzyme Activity
  • Germination and Growth of Seeds Under Different Conditions
  • Microorganisms in Our Surroundings
  • Testing the Effectiveness of Natural Preservatives
  • Study of Human Digestive System Through Models
  • Observing Microscopic Pond Water Organisms
  • Investigating Factors Affecting Heart Rate
  • Comparative Study of Animal and Plant Cells Under Microscope
  • Investigating the Role of Different Soils on Plant Growth

How to Choose Biology Project Ideas?

Choosing biology project ideas can be an exciting yet challenging task. Here are some steps to help you select the perfect project:

#1:- Identify your interests

Start by reflecting on your personal interests within the field of biology. Consider topics or areas that fascinate you and spark curiosity. Whether it’s genetics, ecology, microbiology, or another subfield, selecting a project aligned with your interests will keep you motivated throughout the process.

#2:- Research extensively

Conduct thorough research to explore a wide range of biology project ideas. Read scientific articles, browse biology textbooks, and explore reputable online resources to gather information on various topics. This research phase will help you understand the breadth of possibilities and inspire new ideas.

#3:- Consider available resources

Evaluate the resources at your disposal, such as laboratory equipment, materials, and access to scientific databases . Choose a project that can be realistically executed with the resources you have access to. It’s essential to ensure that your project idea is feasible within the constraints of your available resources.

#4:- Assess the complexity

Consider your grade level and the level of complexity you are comfortable with. Some projects may require advanced techniques or specialized knowledge, while others can be more straightforward and suitable for beginners. Select a project that aligns with your current skill level and academic requirements.

#5:- Set clear objectives

Define clear objectives for your project. What do you want to learn or achieve through this project? Ensure that your objectives are specific, measurable, achievable, relevant, and time-bound (SMART goals). This clarity will guide your project and help you stay focused throughout the process.

#6:- Seek guidance

Consult with your biology teacher, mentor, or other knowledgeable individuals for guidance and feedback. They can provide valuable insights, suggest modifications, or recommend additional resources related to your chosen project idea.

#7:- Consider societal impact

Reflect on the potential societal impact of your project. How does it contribute to scientific knowledge, address real-world issues, or benefit the community? Projects that have broader implications and relevance often make for compelling choices.

Conclusion — Biology Project Ideas

In conclusion, the world of biology is a treasure trove of endless possibilities for captivating and educational projects. By exploring the diverse topics and subfields within biology, you have the opportunity to deepen your understanding of the natural world and develop valuable skills in scientific inquiry and research. 

Whether you choose to investigate genetic variation, delve into the complexities of ecosystems, or explore the hidden world of microorganisms, each project idea holds the potential for exciting discoveries and meaningful contributions to the field. Good luck, and may your biology project be a remarkable experience that sparks a lifelong passion for the wonders of life sciences!

FAQs (Frequently Asked Questions)

What are the 3 science topics.

All three science specialisms – Biology, Chemistry and Physics – are taught in units throughout years 10 and 11.

What is the best topic for a science project?

The best topic for a science project depends on your interests and the scientific principles you want to explore.

What is the best topics for biology project class 10?

“The best topics for a biology project in class 10 could include ‘Human Impact on the Environment,’ ‘Plant Growth and Responses,’ ‘Microorganisms and Disease,’ or ‘Genetics and Heredity.'”

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Top 30 Biology Experiments for High-School

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The field of biology offers a wide range of fascinating experiments that can deepen our understanding of the living world around us. From studying the behavior of cells to investigating the intricacies of ecosystems, biologists use a variety of methods to uncover the secrets of life.

We’ve compiled a captivating list of 30 biology experiments that are both educational and fun and also suitable for a wide range of ages.

These hands-on educational activities will not only deepen your appreciation for the intricacies of life but also fuel your curiosity and passion for scientific exploration.

So, roll up your sleeves, gather your lab equipment, and prepare to embark on an exciting adventure through the fascinating world of biology-based science experiments!

1. Grow a Butterfly

Raise a Butterfly

Students can gain knowledge about the various phases of development, from the egg to the larva to the pupa to the adult butterfly, by studying and taking care of a butterfly during its whole life cycle. This offers students a special chance to learn about the insect life cycle and the metamorphosis process.

Learn more: Elemental Science

2. Dissecting a Flower

Dissecting a Flower

Dissecting a flower can aid students in honing their analytical and observational skills. This may also aid in their comprehension of how a flower’s various components interact to facilitate reproduction, which is the flower’s main objective.

Learn More: How to Dissect a Flower

3. Extracting a DNA

Extracting a DNA

The extraction of DNA is an excellent experiment for high school students to gain a better understanding of the principles of molecular biology and genetics. This experiment  helps students to understand the importance of DNA in research and its applications in various fields, such as medicine, biotechnology, and forensics.

Learn more: Extracting DNA

4. Looking at Fingerprints

Looking at Fingerprints

Exploring fingerprints can be a fun and intriguing experiment. This experiment encourages students to develop their problem-solving skills and attention to detail, as they must carefully analyze and compare the various fingerprint patterns.

Fingerprint analysis is a fascinating and engaging experiment that can spark an interest in forensic science and provide students with a hands-on learning experience.

Learn more: Directions to Examine a Fingerprint

5. Cultivate Bacteria on Home Made Agar

Cultivate Bacteria on Home Made Agar

This experiment provides a hands-on learning experience for students to understand the principles of microbiology and the techniques used in bacterial culture.

This experiment can also help students to understand the importance of bacteria in our daily lives, their role in human health, and their applications in various fields, such as biotechnology and environmental science.  

Learn more: Grow bacteria on Homemade Agar Plates

6. Make a Bioluminescent Lamp

Make a Bioluminescent Lamp

This experiment provides an excellent opportunity for high school students to learn about bioluminescence and the principles of genetic engineering.

Creating a bioluminescent lamp is a fun and engaging way to explore the intersection of biology, chemistry, and physics, making it a perfect experiment for students interested in science and technology.

Learn more: Make Glowing Water

7. Make Plants Move with Light

Make Plants Move with Light

This experiment can help students understand the role of light in plant growth and photosynthesis and the importance of light as an environmental factor for plant survival. 

Learn more: Experiments with Phototropism

8. Test the Five-Second Rule

Test the Five-Second Rule

The “5-second rule” experiment is a simple and fun way to investigate the validity of the popular belief that it is safe to eat food that has been dropped on the ground for less than 5 seconds.

The experiment is an engaging and informative way to explore the science behind a common belief and promote critical thinking and scientific inquiry among students.

Learn more: Five Second Rule

9. Examine How Antibiotics Affect Bacteria

Examine How Antibiotics Affect Bacteria

This experiment is an excellent opportunity for high school students to develop their laboratory skills, such as aseptic technique and bacterial culture, and understand the principles of antibiotic resistance and its implications for human health.

Examining how antibiotics affect bacteria is a fascinating and educational experiment that promotes scientific inquiry and critical thinking among students.

Learn more: Learn About Bacteria

10. Look for Cell Mitosis in an Onion

Look for Cell Mitosis in an Onion

This experiment is an excellent opportunity for high school students to develop their microscopy skills and understand the biological basis of growth and development in plants. This experiment is a fun and informative way to explore the world of cells and their role in the growth and development of living organisms.

Learn more: Onion Root Mitosis

11. Test the Effects of Disinfectants

Test the Effects of Disinfectants

Testing the effects of disinfectants is an important process in determining their efficacy in killing or reducing the number of microorganisms on a surface or object. Disinfectants can be hazardous if not used correctly, and testing their effects can help students understand how to use them safely.

Students can learn about proper handling techniques and how to interpret safety labels and warning signs.

Learn more: Antiseptic and Disinfectants

12. Microwave Seed Gardening

Microwave Seed Gardening

Microwave seed gardening is a quick and efficient method of germinating seeds, microwave seed gardening can be a useful method for starting seeds, but it should be used with care and in conjunction with other germination methods to ensure the best possible results. 

Learn more: Microwave plant

13. Water Bottle Bacteria Swab

Water Bottle Bacteria Swab

This experiment can be a fun and informative way to learn about the importance of keeping water bottles clean and free from harmful bacteria. It can also be used to compare the cleanliness of different types of water bottles, such as metal, plastic, or glass.

Learn more: Swabbing Water Bottles

14. Frog Dissection

Frog Dissection

Frog dissection can be a valuable tool for teaching anatomy and physiology to high school students, as it provides a comprehensive examination of the internal organs and systems of the frog.

Dissection can be a valuable and engaging experiment for high school students interested in biology and life science.

Learn more: Frog Dissection

15. Witness the Carbon Cycle in Action

Witness the Carbon Cycle in Action

By witnessing the carbon cycle in action, learners can gain a better understanding of the interconnectedness of different parts of the Earth’s system and the impact that human activities can have on these processes.

Learn more: Carbon Cycle Lab

16. Investigate the Efficacy of Types of Fertilizer

Investigate the Efficacy of Types of Fertilizer

Investigating the efficacy of different types of fertilizer can be an interesting and informative way to learn about plant growth and nutrition. Investigating the efficacy of different types of fertilizer is a practical and engaging way to learn about plant nutrition and the role of fertilizers in agriculture.

Learn more: Best Fertilizer

17. Explore the Impact of Genetic Modification on Seeds

Explore the Impact of Genetic Modification on Seeds

Exploring the impact of genetic modification on seeds is a fascinating and relevant topic that can spark meaningful discussions and encourage learners to think critically about the role of science and technology in society.

Learn more: Genetically Modified (GM) Crops

18. Yeast Experiment

Yeast Experiment

Another easy to perform experiment for high school students is the yeast. This experiment is simple since all that is required is the removal of four different food samples onto separate plates and a thorough examination of the mold that develops on each sample over time.

Learn more: Grow Yeast Experiment

19. Taste Perception 

Taste Perception

The human tongue has specialized taste receptors that respond to five primary tastes: sweet, salty, sour, bitter, and umami (savory). Taste perception plays an important role in determining food preferences and dietary habits, as well as influencing the overall eating experience.

Learn more: Taste perception

20. Pea Plant Genetics

Pea Plant Genetics

A classic pea plant genetics experiment involves cross breeding pea plants with different traits, such as flower color, seed shape, or pod shape.

This experiment can be conducted in a controlled environment, such as a greenhouse, by manually transferring pollen from one plant to another.

Learn more: Gregor Mendel Pea Experiment

21. Comparing Animal and Plant Cells

Comparing Animal and Plant Cells

Comparing animal and plant cells is an important exercise in biology education. Both animal and plant cells are eukaryotic cells, meaning they contain a nucleus and other membrane-bound organelles.

This exercise can help students understand the structure and function of cells, as well as appreciate the diversity of life on Earth.

Learn more: Comparing Plant Cell and Animal Cell

22.  Testing Bacteria 

 Testing Bacteria 

Bacteria are easily accessible and can be grown in a laboratory or even at home with simple equipment and materials. This makes it a practical and cost-effective experiment for schools with limited resources.

Learn more: How to grow Bacteria and more

23. The Effect of Light on Growth

The Effect of Light on Growth

Light is a fundamental environmental factor that plays a crucial role in the growth and development of plants. By conducting this experiment, students can gain a deeper understanding of how light affects plant growth and why it is important.

Learn more: The effect of light in Plant Growth

24. Planaria Regeneration

Planaria Regeneration

Planaria regeneration allows students to design their own experiments, as they can choose which body parts to remove and study the effects of different variables, such as temperature, pH, or chemical treatments on the regeneration process.

Planaria are easy to obtain and maintain in a laboratory or classroom setting. They are also affordable, making it an ideal experiment for schools with limited resources.

Learn more: Planaria Experiment

25. Making a Seed Board

Making a Seed Board

Making a seed board can be a fun and engaging activity for students, as they can see the progress of their plants over time and share their results with others. It can also foster a sense of responsibility and ownership in caring for their plants.

26. Design an Owl Pellet

Design an Owl Pellet

Dissecting an owl pellet provides a hands-on learning experience for students, allowing them to practice skills in scientific observation, data collection, and analysis. Students can also learn about the anatomy of the prey species found in the owl pellet.

27. Grow an Herbal Cutting

Grow an Herbal Cutting

Growing an herb cutting provides a hands-on learning experience for students, allowing them to practice skills in plant care, experimental design, and data collection. Students can learn about the different stages of plant growth and the factors that affect it.

28. Eat a Cell Model

Eat a Cell Model

Creating an edible cell model connects to various disciplines, such as biology, anatomy, and nutrition. Students can learn about the different organelles that make up a cell and their functions, as well as the nutritional value of the food materials used in the model

29. Make a Habitat Diorama

Make a Habitat Diorama

Making a habitat diorama provides a hands-on learning experience for students, allowing them to practice skills in research, creative design, and presentation. Students can learn about different ecosystems and the organisms that inhabit them.

30. Create a Fall Leaf (or Signs of Spring) Journal

Create a Fall Leaf (or Signs of Spring) Journal

Creating a fall leaf (or signs of spring) journal provides a hands-on learning experience for students, allowing them to practice skills in observation, data collection, and analysis. Students can learn about the changes that occur in nature during the fall or spring season.

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4 Biology Project Ideas for High School Students

Biology Projects are great teaching tools educators can use to boost student interest in the subject and spark classroom participation.

Testing plants and gravity

Testing root growth in relationship to gravity is a fun and simple idea. To do this, students need to cut a strip of paper towel approximately one inch wide. Then, they lay pinto beans on the strip and roll it up. Next, moisten the strip and tape it to a square of cardboard, placing the entire thing in a zip top bag. Finally, place it in a warm window and observe over time and look for roots and stems to sprout.

Once the roots and stems sprout, students will notice that the sprouts point up and the roots point down. After making this observation, students should turn the bag so the plant is growing sideways, then upside down, continuing to observe root growth with these changes

Fruit flies and tea

Tea is often offered as a healthful drink, but which tea is the most healthful? This project tries to answer that. To set up the fruit fly and tea experiment, students must create a mixture of tea and fruit fly food. This works best when students choose four different teas to test four different groups of flies. A fifth group — the control group — will receive fruit fly food with plain water. The tea should be brewed by seeping a tea bag in three tablespoons of boiling water for a set period of time. Then, it should be mixed with fruit fly food.

Once the food is prepared, it should be added to five separate vials. Then, each vial receives 10 adult fruit flies. Every day, the fruit flies that remain alive should be removed and transferred to a new vial that contains the same tea and food mixture. This should be repeated until all fruit flies have died. The student can then determine which food/tea mixture provided the greatest longevity to the flies.

Cleaning oil off birds

When birds are coated with oil after an oil spill, their life is at risk. This project will test a variety of solvents to determine which is the best to use in this situation. It uses feathers, not live birds, to make this determination.

The experiment begins with weighing several sets of feathers, then dipping bird feathers in oil. After the feathers are dipped, they are weighed again. This shows the weight of the oil on the feathers and serves as the means of measuring the effectiveness of the solvents.

Once they are all dipped and weighed, the feathers are washed in a range of cleaners, with one group remaining unwashed to serve as a control. After washing, the feathers are weighed yet again. This should indicate which solvent is the most effective, as the feathers washed in it will show the most oil weight loss.

Vitamin C and colds

Vitamin C is often offered as a solution to help prevent the common cold. This simple experiment helps determine if there is much fact to this common bit of advice. The student selects two groups of willing participants, preferably people who do not live in the same house. One group will agree to take a vitamin C tablet daily for a month, while the second will agree not to. All will record any cold symptoms they experience during that month.

At the end of the month, the groups will switch. After a second month, the data can be collected and analyzed to determine if taking vitamin C made a difference in cold symptoms.

Each of these biology project ideas tackles a different aspect of the subject, including botany, environmental science, human biology and zoology. They all provide an interesting way to present important biology ideas to students in a way that encourages inquiry.

20 Fun and Interesting Biology Experiments for High School 

Jennifer is a prolific writer with over 10 years of experience in online writing. She enjoys creating quotes and poems.

Learn about our Editorial Policy .

Unlike science in middle school, high school biology is a hands-on endeavor. Experiments are a standard part of biology courses, whether they are part of a controlled laboratory class, science fair, or individual student projects. Explore a few fascinating high school biology experiments; and discover ideas for simple and easy biology experiments to incorporate into your curriculum.

Examples of Biology Experiments for High School

Whether you are looking for a science fair project or need to create a project for a class assignment, there are numerous biology projects for teens.

  • 21 Unique High School Yearbook Themes and Ideas Teens Will Love
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Frog Dissection

Dissecting a frog is a quintessential part of high school biology. If possible, try to get both female and male specimens for your class so students can see the eggs and compare the insides to the male frog.

Flower Dissection

High schoolers can get a bit squirmy about frog dissection. Have a flower dissection instead. The teens can find and label the female and male parts of the flower. It can be fun for high schoolers to check out flower intricacies under a microscope.

Diversity Among Plant Samples

Another simple biology experiment involves going into your natural environment, such as a local park, to observe diversity among plant samples. To make the experiment more detailed, students can rub collected samples on filter paper to observe which plants present which colors . Teens can work to find out why certain plants present certain colors.


It can be enlightening to show kids how phototropism affects plants. They can set up an experiment by using different materials to affect light. They can see how affecting the light affects the growth of the plant.

Water From Common Sources

Water is everywhere. Unfortunately, water contains numerous elements too. A great experiment is collecting water samples from various sources and viewing them under a microscope. Students can then compare their results and attempt to postulate why a given water source would present more organisms than another would.

Yeast Experiment

Another experiment involves taking a piece of bread to monitor the molds that grow over a period of two weeks.

Taste Perception

Everyone has their own taste. Literally! Some people like sour things while others like sweet. Find out if everyone perceives taste the same way and has the same threshold for taste by doing an in-class experiment.

Disinfectant Effectiveness

Ever wonder how effective hand sanitizer is at killing bacteria? Test it! Grow bacteria in a Petri dish along with paper soaked in peroxide, white vinegar, rubbing alcohol, etc. Find out how each one of them works to inhibit bacteria growth.

Pea Plant Genetics

Students can recreate Mendel's genetic pea plant experiments . By growing pea plants and comparing their phenotypes, students can determine each parent plant's genotype.

Examining Fingerprints

Fingerprints are pretty amazing features on the human body. Not only can you use them to open your phone, but each one is unique . Put your fingerprint on paper and examine the different aspects of the lines and arches on your fingers. Compare fingerprints among everyone in class.

Comparing Animal and Plant Cells

To better understand animal and plant cells, students can compare cells from their cheeks to cells from an onion. Just stain the cells with iodine or another dye to better see the cell structures under a microscope.

Creating a DNA model is a great way to help students understand the structure and function of DNA in genetics. Students can use candy, string, and toothpicks to develop a fairly realistic model of the double helix structure.

Water Bottle Germs

Many people refill their water bottles in high school. But do they add germs or bacteria to the bottle? Is refilling a disposable water bottle safe? Have students take swabs of the water bottles they use and look for bacteria around the lid or on the bottle.

Testing Hair

Teens use a lot of hair products. But do they truly work? Have teens in your class take a few samples of their hair. See what happens to the hair when common hair products are added.

Water Cycle

Understanding the water cycle isn't hard. But teens can look at it firsthand by creating a water cycle experiment. Just have them fill a baggie with water and tape it to a window. They will watch evaporation, condensation, and precipitation in action.

Closed Ecosystem Bottle

It can be hard for students to imagine something having its own ecosystem. However, you can use a plastic bottle to create a closed ecosystem.

Field Survey Biology Experiment

This experiment is great because it is cheap, easy, and you can do it in a variety of areas around your school or send students home with it. The goal is to observe the surrounding area over time and monitor the samples that you collect.

Materials You'll Need

For this experiment, you need to grab:

  • Jar or baggies to collect samples
  • Stakes and string or cones help mark an area
  • Paper or journals for taking notes
  • Slides, slide covers, and a microscope

Observation Instructions

Take note that you will observe your area for several months, so choose an area that is easy to re-mark or where you can leave the markings up, so you return to the same designated area each time.

  • Have students choose one spot to observe. The spot should be no more than two to three feet square.
  • Do you see evidence of animals? (Look for prints, scat or guano, fur, owl pellets, etc.)
  • What plant life do you see? (Look for moss, lichen, weeds, and other plants).
  • What fungus do you see? (Look for mushrooms and other fungal growth).
  • What insects do you see? (Encourage students to look specifically for relationships here - such as connecting mosquitos with water or bees with flowers or a hive).

Sampling and Classroom Instructions

Bring the research back into the classroom by following these instructions.

  • Guide students to make connections and note relationships in their marked area. Have them inventory the area and draw a crude map of where everything is.
  • If possible, have students use tweezers and gently take samples of soil, fungus, moss, plant life, insects, etc.
  • pH value of soil or water
  • Microorganisms in water
  • Plant cells under a microscope
  • Comparative structure of flowers you find
  • Require students to record everything in their own journal or interactive notebook.

Teacher tip: Set up stations in the classroom for viewing, dissecting, drawing, testing pH, etc. This will allow students some choice in how they proceed with examining their specimens.

Testing for Bacteria

Have students see where the most bacteria are lurking. This experiment is great if you want a lab that has guaranteed results. There is always some kind of bacteria lurking somewhere, just waiting to grow in a student's Petri dish.

These are the materials you are going to need to have on hand.

  • Prepared Petri dishes, three per student
  • Sterile swabs
  • Painter's tape
  • Scotch tape
  • Permanent Marker
  • Graph paper

Material notes : You can also purchase sterile Petri dishes and agar separately; however, it is much more likely students will contaminate the plate before they swab.

Preparing Your Petri Dishes

Prepping your Petri dishes is an essential part of the experiment.

  • Before opening any materials, have students identify three places (but in one physical location such as at home or at school) that they are going to swab for bacteria. Encourage them to hypothesize about which place they think will grow the most bacteria.
  • Using the Petri dish, trace three circles on the graph paper and cut it out.
  • In pencil, draw a line to denote the 'top' of the circle. It doesn't matter where you draw the line, but you will need something to show you how your Petri dish is oriented so you can be sure you're tracking the same colony each time you observe.
  • On the back of the graph paper circle, note the location where you will take the swab, as well as the date you are taking the swabs. Do this for all three Petri dishes you have.

Collecting Samples

Have students bring their unopened sterile swabs and closed Petri dishes to the site. Carefully, they should:

  • Set the Petri dish down on a flat surface.
  • Unwrap the swab.
  • Swipe the swab across the area they suspect has bacteria.
  • Lift the lid, gently wipe the used swab across the agar, and close the lid, carefully but quickly.

Hint: Sometimes, it's helpful to tape the Petri dish shut so that the Petri dish doesn't accidentally lose its lid.

Evaluating Results

Now that you've swabbed the areas, it's all about the results.

  • Have students draw Petri-dish-sized circles in their lab books or on separate graph paper. Draw one week's worth of Petri dishes for each dish the student has.
  • As the colonies start to grow, have students draw the size in their notebooks, making daily observations. If they cannot observe daily, have them observe on the same day(s) over a month.
  • They should also be recording the color and other notable features of their bacteria colonies in their lab books.
  • At the end, the students should write a conclusion of their study.

The Effect of Light on Growth

In this lab, students investigate how light affects plant growth. Students may use any plants, but cress will grow more quickly, so your students can get results faster.

Gather up your materials.

  • Styrofoam cup or bowl
  • Potting soil


With your materials at the ready, it's time to start your experiment.

  • On Day 1 - plant seeds in the soil in the cups.
  • Label the cups according to the light you're going to use. You can compare sunlight vs. complete darkness, or you can compare several types of light.
  • On each day after the initial day, take a picture of each cup and try to measure the growth, if any.
  • For your lab entries, measure the sprouts, and note color and shape characteristics.

Planaria Regeneration

In this lab, students watch the rate at which planaria regenerates and test whether how you cut the planaria makes a difference as to how they grow back.

To conduct this experiment, you want to grab.

  • 9 planarias
  • 3 small plastic Petri dishes
  • 1 large plastic Petri dish
  • 1 plastic pipet
  • 1 magnifying glass
  • 1 plastic coverslip
  • Spring water
  • Paper towels
  • Ice pack(optional)

Setup Instructions

Getting the setup right is half the battle when it comes to creating fun and interesting biology experiments for high schoolers.

  • Start by numbering the three small Petri dishes to ensure nothing gets confused later.
  • Using the pipet, move a planarian into the large Petri dish.
  • At this point, you may want to try to set the Petri dish on an ice pack for a few minutes. This isn't totally necessary, but it will slow the planarian down to make it easier to cut.
  • Right behind the head
  • Right in the middle
  • Right towards the tail
  • Use the pipet to gently transfer each segment to a new Petri dish (with spring water).
  • Repeat the steps with all remaining worm segments.
  • Every day, observe the planaria. Regeneration will be considered 'complete' when the photoreceptors (the black dots that look like eyes on the planarian's head) appear.

Scientific Method and High School Biology Experiments

Much of high school biology is focused on instilling the elements of science in students. The scientific method is one of these main focuses. The method prompts participants in science to be investigators and to come up with a guess about what will happen in a given experiment, called a hypothesis. The point of the experiment is then to either prove the hypothesis correct through the experiment or prove it incorrect. This prompts teens to get involved in the scientific method while teaching other scientific skills, such as:

  • The ability to make a rational estimate based on present factors and knowledge
  • Close detail and monitoring skills
  • The possibility of being wrong and how to move past that if it turns out to be the case
  • Quick thinking skills

As much fun as biology experiments can be, there is an educational component spearheading the experiment.

Fun and Interesting High School Biology Experiments

For teens, high school biology can be fun. Finding the right experiment can help biology pop off the page and become more than just another required course of study. Who knows? Perhaps your student will even be prompted to enter a science fair or a career rooted in science?

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Biology Experiment Ideas for High School

Published on Sep 12, 2023

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55 Best Science Experiments for High School Labs and Science Fairs

Fire up the Bunsen burners!

High school science experiments, including racing a 3-d printed car carrying broccoli and removing air from a DIY vacuum chamber

The cool thing about high school science experiments and projects is that kids are old enough to tackle some pretty amazing concepts. Some science experiments for high school are just advanced versions of simpler projects they did when they were younger, with detailed calculations or fewer instructions. Other projects involve fire, chemicals, or other materials they couldn’t use before.

Many of these science experiments for high school are intended for classroom labs, but most can be adapted to become science fair projects too. Just consider variables that you can change up, like materials or other parameters. That changes a classroom lab into a true scientific method experiment!

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Biology Experiments for High School

When it comes to biology, science experiments for high school students usually bring dissection to mind. But there are plenty of other useful labs and hands-on projects for teens to try. Here are some of our favorites.

1. Mash potatoes to learn about catalase

Three test tubes in a red holder, filled with a white substance

Catalase is found in nearly all living cells, protecting them from oxidative damage. Try this lab to isolate catalase from potatoes using hydrogen peroxide.

Learn more: Potato Catalase/Practical Biology

2. Extract DNA from a strawberry

Collage of steps to extract DNA from a strawberry (Science Experiments for High School)

You don’t need a lot of supplies to perform this experiment, but it’s impressive nonetheless. Turn this into a science fair project by trying it with other fruits and vegetables too.

Learn more: Strawberry DNA/Numbers to Neurons

3. Re-create Mendel’s pea plant experiment

Pea plants growing in white square containers on a lab table

Gregor Mendel’s pea plant experiments were some of the first to explore inherited traits and genetics. Re-create his cross-pollination experiments with a variety of pea plants you’ve grown yourself.

Learn more: Mendel’s Pea Plants/Love to Know

4. Make plants move with light

Diagram of plant seedlings moving toward light affected by different variables (Science Experiments for High School)

By high school age, kids know that many plants move toward sunlight, a process known as phototropism. So science experiments for high school students on this topic need to introduce variables into the process, like covering seedling parts with different materials to see the effects.

Learn more: Phototropism/Science Buddies

5. Test the five-second rule

We’d all like to know the answer to this one: Is it really safe to eat food you’ve dropped on the floor? Design and conduct an experiment to find out (although we think we might already know the answer).

6. Taste foods to find your threshold for sour, sweet, and bitter

Human tongue with an arrow pointing to the papillae

The sense of taste is fascinating—what some people think is delicious, others just can’t stand. Try this experiment to test subjects’ taste perceptions and thresholds using a series of diluted solutions.

Learn more: Taste Threshold/Science Buddies

7. Complete a field survey

Students examining the water in a ditch in a green field (Science Experiments for High School)

Teaching students to conduct field surveys opens up the possibility of lots of different science experiments for high school. Show them how to observe an area over time, record their findings, and analyze the results.

Learn more: Field Survey/Love to Know

8. See the effects of antibiotics on bacteria

Test tubes containing various bacteria

Bacteria can be divided into two groups: gram-positive and gram-negative. In this experiment, students first determine the two groups, then try the effects of various antibiotics on them. You can get a gram stain kit , bacillus cereus and rodospirillum rubrum cultures, and antibiotic discs from Home Science Tools.

Learn more: Antibiotics Project/Home Science Tools

9. Witness the carbon cycle in action

Test tubes filled with plants and green and blue liquid

We know that plants take in carbon dioxide and give off oxygen, right? Well, this experiment helps you prove that and see the effect light has on the process.

Learn more: Carbon Cycle/Science Lessons That Rock

10. Look for cell mitosis in an onion

Cell mitosis (division) is actually easy to see in action when you look at onion root tips under a microscope. Students will be amazed to see science theory become science reality right before their eyes.

11. Test the effects of disinfectants

Petri dish divided in half with bacteria and paper disks on the surface

Grow bacteria in a petri dish along with paper disks soaked in various antiseptics and disinfectants. You’ll be able to see which ones effectively inhibit bacteria growth.

Learn more: Antiseptics and Disinfectants/Amy Brown Science

12. Investigate the efficacy of types of fertilizer

How to choose the fertilizer that will make plants grow the fastest.

Let’s spice things up in the botanical kitchen! Mix up some “recipes” for your students’ plants by experimenting with different types of fertilizer and see which one they devour the most.

Learn more: Best Fertilizer/

13. Explore the impact of genetic modification on seeds

Competition between crops and weeds and introduction of genetically modified seeds

Let’s go green and see what happens when we pit our crops against some weeds! Will genetically modified plants come out on top or will the weeds reign supreme? Let’s find out in this exciting biotech and plant challenge!

Learn more: Genetically Modified Seeds/Science Buddies

Chemistry Experiments for High School

Perhaps no class is better suited to science experiments for high school kids than chemistry. Bunsen burners, beakers and test tubes, and the possibility of (controlled) explosions? Students will love it!

14. Watch a beating heart made of gallium

Blob of gallium with the image of a beating heart and the periodic table symbol for gallium

This is one of those science demos that’s so cool to see in action. An electrochemical reaction causes a blob of liquid metal to oscillate like a beating heart!

Learn more: Gallium Demo/Science Notes

15. Break apart covalent bonds

Tub of water with battery leads in it

Break the covalent bond of H 2 O into H and O with this simple experiment. You only need simple supplies for this one.

Learn more: Covalent Bonds/Teaching Without Chairs

16. Measure the calories in various foods

Collage of steps for measuring calories with a homemade calorimeter (Science Experiments for High School)

How do scientists determine the number of calories in your favorite foods? Build your own calorimeter and find out! This kit from Home Science Tools has all the supplies you’ll need.

Learn more: DIY Calorimeter/Science Buddies

17. Detect latent fingerprints

Fingerprint divided into two, one half yellow and one half black

Forensic science is engrossing and can lead to important career opportunities too. Explore the chemistry needed to detect latent (invisible) fingerprints, just like they do for crime scenes!

Learn more: Fingerprints/HubPages

18. Use Alka-Seltzer to explore reaction rate

Collage of reaction rate experiment steps (Science Experiments for High School)

Tweak this basic concept to create a variety of science experiments for high school students. Change the temperature, surface area, pressure, and more to see how reaction rates change.

Learn more: Reaction Rate/Numbers to Neurons

19. Determine whether sports drinks provide more electrolytes than OJ

Open circuit equipment for testing for electrolytes (Science Experiments for High School)

Are those pricey sports drinks really worth it? Try this experiment to find out. You’ll need some special equipment for this one; buy a complete kit at Home Science Tools .

Learn more: Electrolytes Experiment/Science Buddies

20. Extract bismuth from Pepto-Bismol

Piece of bismuth extracted from Pepto Bismol

Bismuth is a really cool metal with a rainbow sheen. It’s also an ingredient in Pepto-Bismol, and by carefully following the procedures at the link, you can isolate a chunk of this amazing heavy metal.

Learn more: Extracting Bismuth/Popular Science

21. Turn flames into a rainbow

You’ll need to get your hands on a few different chemicals for this experiment, but the wow factor will make it worth the effort! (Click through to the YouTube link for an explanation of how this one works.)

22. Test and sort elements

Students using electrical circuits to test items in a petri dish (Science Experiments for High School)

Elements in the periodic table are grouped by metals, nonmetals, and metalloids. But how do chemists determine where each element belongs? This ready-to-go science kit contains the materials you need to experiment and find out.

Learn more: Metals, Nonmetals, and Metalloids/Ward’s Science

23. Discover the size of a mole

Supplies needed for mole experiment, included scale, salt, and chalk

The mole is a key concept in chemistry, so it’s important to ensure students really understand it. This experiment uses simple materials like salt and chalk to make an abstract concept more concrete.

Learn more: How Big Is a Mole?/Amy Brown Science

24. Cook up candy to learn mole and molecule calculations

Aluminum foil bowl filled with bubbling liquid over a bunsen burner

This edible experiment lets students make their own peppermint hard candy while they calculate mass, moles, molecules, and formula weights. Sweet!

Learn more: Candy Chemistry/Dunigan Science TpT

25. Make soap to understand saponification

Colorful soaps from saponification science experiments for high school

Take a closer look at an everyday item: soap! Students use oils and other ingredients to make their own soap, learning about esters and saponification.

Learn more: Saponification/Chemistry Solutions TpT

26. Uncover the secrets of evaporation

This systematic and classic example of changing one variable at a time by creating several mini-projects will have your high schoolers engaged in a high-level review of the classic scientific method.

Learn more: Evaporation/Science Projects

27. Investigate the principles of pyrotechnics

Explore how fireworks work - a high school chemistry experiment.

Let’s dive into the explosive world of fireworks and discover the colorful secrets behind these dazzling pyrotechnic displays! Your students will be ecstatic to use party poppers (and sparklers, if you’re feeling really daring) to explore the science behind fireworks.

Learn more: How Fireworks Work/Royal Society of Chemistry

Physics Experiments for High School

When you think of physics science experiments for high school, the first thing that comes to mind is probably the classic build-a-bridge. But there are plenty of other ways for teens to get hands-on with physics concepts. Here are some to try.

28. Remove the air in a DIY vacuum chamber

DIY vacuum chamber made from a jar and large hypodermic needle

You can use a vacuum chamber to do lots of cool experiments, but a ready-made one can be expensive. Try this project to make your own with basic supplies.

Learn more: Vacuum Chamber/Instructables

29. Put together a mini Tesla coil

Looking for a simple but showy high school science fair project? Build your own mini Tesla coil and wow the crowd!

30. Boil water in a paper cup

Logic tells us we shouldn’t set a paper cup over a heat source, right? Yet it’s actually possible to boil water in a paper cup without burning the cup up! Learn about heat transfer and thermal conductivity with this experiment. Go deeper by trying other liquids like honey to see what happens.

31. Blast music using magnets

A paper speaker built from magnets, cardboard, and a paper plate

We spend a lot of time telling teens to turn down their music, so they’ll appreciate the chance to turn it up for once! Using strong magnets and an amplifier (both available on Amazon), plus a few other supplies, they’ll build a speaker and measure how the magnets affect the volume.

Learn more: Paper Speaker/Science Buddies

32. Construct a light bulb

Emulate Edison and build your own simple light bulb! You can turn this into a science fair project by experimenting with different types of materials for filaments.

33. Measure the speed of light—with your microwave

Student measuring the distance between holes in cooked egg whites (High School Science Experiments)

Grab an egg and head to your microwave for this surprisingly simple experiment! By measuring the distance between cooked portions of egg whites, you’ll be able to calculate the wavelength of the microwaves in your oven, and in turn, the speed of light.

Learn more: Microwave Speed of Light/Science Buddies

34. Generate a Lichtenberg figure

Lichtenberg figure generated on a sheet of Plexiglassd in

See electricity in action when you generate and capture a Lichtenberg figure with polyethylene sheets, wood, or even acrylic and toner. Change the electrical intensity and materials to see what types of patterns you can create.

Learn more: Lichtenberg Figure/Science Notes

35. Build your own Newton’s Cradle

Student swinging the right ball on a DIY Newton's Cradle made of popsicle sticks and marbles

Newton’s Cradle demonstrates the concept of momentum—and it’s really fun to play with! Challenge students to design and build their own, experimenting with different materials or changing up the number of balls to see how it affects momentum.

Learn more: How To Make a Simple Newton’s Cradle/Babble Dabble Do

36. Explore the power of friction with sticky note pads

A wood platform holding a weight suspended by chains from two sticky note pads interleaved together (Science Experiments for High School)

Ever try to pull a piece of paper out of the middle of a big stack? It’s harder than you think it would be! That’s due to the power of friction. In this experiment, students interleave the sheets of two sticky note pads, then measure how much weight it takes to pull them apart. The results are astonishing!

Learn more: Sticky Notes Friction/Science Buddies

37. Bounce balls to explore stored energy and energy transfer

Colorful rubber balls bouncing against a white background

Learn about potential and kinetic energy by bouncing balls and measuring their heights on each rebound. This is one of those classic physics science experiments for high school that students are sure to enjoy!

Learn more: Rebound Experiment/Science Buddies

38. Build a cloud chamber to prove background radiation

A cloud chamber constructed of a plastic container, cookie sheet, and dry ice, and

Ready to dip your toe into particle physics? Learn about background radiation and build a cloud chamber to prove the existence of muons.

Learn more: Background Radiation/Science Buddies

39. Slide into kinetic friction

Measure the effect of friction on different surfaces.

Students will investigate kinetic friction and its effects on the speed of a rolling object by giving the objects a little push and watching them fly, on surfaces both smooth and rough. Stay tuned to see which texture wins the race!

Learn more: Effect of Friction on Objects in Motion/Science Buddies

40. Harness the power of air drag

Design and test parachutes to study air drag.

Who can make the slowest descent? Students will use the power of drag to create a design that takes its sweet time falling to the ground. They’ll be encouraged to tinker and tweak until they have the ultimate sky-sailing machine.

Learn more: Science World and Scientific American

41. Magnetize a motor

5 high school physics science projects with magnets.

Magnets lend themselves as a helpful material in many a science experiment. Your students will explore the properties of magnetism with any one of these five experiments using magnets. They’ll even learn the basics of Fleming’s left-hand rule.

Learn more: Simple Electric Motor/School Science Experiments

42. Explore interference and diffraction

Explore interference and diffraction using CDs.

Investigate the physics of light and optics using CDs and DVDs. Though both of these optical objects might be quickly becoming a thing of the past, your students can utilize their diffraction patterns to explore the science behind optics.

Learn more: Science Buddies

Engineering Experiments for High School

Engineering involves the hands-on application of multiple types of science. Teens with an interest in designing and building will especially enjoy these STEM challenge science experiments for high school. They’re all terrific for science fairs too.

43. Re-create Da Vinci’s flying machine

Da Vinci flying machine built from a paper cup and other basic supplies

Da Vinci sketched several models of “flying machines” and hoped to soar through the sky. Do some research into his models and try to reconstruct one of your own.

Learn more: Da Vinci Flying Machine/Student Savvy

44. Peer into an infinity mirror

Rectangular and circular mirrors with lights reflecting into the distance (Science Experiments for High School)

Optical illusions are mesmerizing, but they also help teach kids about a variety of science concepts. Design and build a mirror that seems to reflect lights on and on forever. The supplies are basic, but the impact is major!

Learn more: Infinity Mirror/Science Buddies

45. Design a heart-rate monitor

DIY heart rate monitor made from blue fabric and a red heart

Smartwatches are ubiquitous these days, so pretty much anyone can wear a heart-rate monitor on their wrist. But can you build your own? It takes some specialized supplies, but they’re not hard to track down. You can buy items like an Arduino LilyPad Board on Amazon.

Learn more: Heart Rate Monitor/Science Buddies

46. Race 3D printed cars

Simple 3-D printed race cars with vegetables strapped to them (Science Experiments for High School)

3D printers are a marvel of the modern era, and budding engineers should definitely learn to use them. Use Tinkercad or a similar program to design and print race cars that can support a defined weight, then see which can roll the fastest! (No 3D printer in your STEM lab? Check the local library: Many of them have 3D printers available for patrons to use.)

Learn more: 3D Printed Cars/Instructables

47. Launch a model rocket

Model rockets built from water bottles and other supplies

Bottle rockets are another one of those classic science experiments for high school classes, and for good reason! The engineering involved in designing and launching a rocket capable of carrying a specified payload involves the practical application of all sorts of concepts. Plus, it’s fun!

Learn more: Bottle Rockets/Science Buddies

48. Grow veggies in a hydroponic garden

Vertical hydroponic garden made from PVC pipes and aluminum downspouts

Hydroponics is the gardening wave of the future, making it easy to grow plants anywhere with minimal soil required. For a science fair engineering challenge, design and construct your own hydroponic garden capable of growing vegetables to feed a family. This model is just one possible option.

Learn more: Hydroponics/Instructables

49. Grab items with a mechanical claw

KiwiCo hydraulic claw kit (Science Experiments for High School)

Delve into robotics with this engineering project! This kit includes all the materials you need, with complete video instructions.

Learn more: Hydraulic Claw/KiwiCo

50. Play volleyball with machines

Challenge your students to design and build machines that will volley a Ping-Pong ball back and forth, using only basic materials. They can even compare their results to those from students around the world!

Learn more: Volleyball Challenge/Science Buddies

51. Construct a crystal radio

Homemade crystal radio set (Science Experiments for High School)

Return to the good old days and build a radio from scratch! This makes a cool science fair project if you experiment with different types of materials for the antenna. It takes some specialized equipment, but fortunately, Home Science Tools has an all-in-one kit for this project.

Learn more: Crystal Radio/SciToys

52. Build a burglar alarm

Simple electronic burglar alarm with a cell phone

The challenge? Set up a system to alert you when someone has broken into your house or classroom. This can take any form students can dream up, and you can customize this STEM high school science experiment for multiple skill levels. Keep it simple with an alarm that makes a sound that can be heard from a specified distance. Or kick it up a notch and require the alarm system to send a notification to a cell phone, like the project at the link.

Learn more: Intruder Alarm/Instructables

53. Walk across a plastic bottle bridge

Students sitting on a large bridge made of plastic bottles

Balsa wood bridges are OK, but this plastic bottle bridge is really impressive! In fact, students can build all sorts of structures using the concept detailed at the link. It’s the ultimate upcycled STEM challenge!

Learn more: TrussFab Structures/Instructables

54. Unleash the power of geothermal energy

How to use heat as a source of renewable energy.

This experiment is all about tapping into the fiery fury deep underground within the Earth and harnessing it for clean, renewable power. It will definitely spark your students’ interest and exploration of geothermal energy.

Learn more: Geothermal Energy/Science Buddies

55. Construct a Rube Goldberg machine

In this activity, students will unleash their creativity as they design and build their very own contraptions that perform a simple task in the most complicated way possible. Your students will be using the engineering design process, problem-solving skills, and teamwork to create truly unique machines.

Learn more: Design and Build a Rube Goldberg/Teach Engineering

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Whether you're a student looking for a science fair idea or a teacher seeking new science experiments for high school labs, find them here!

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